91026-00-5

Basic information

• Product Name: N-BENZYL-2 3-DIBROMOMALEIMIDE 97
• Synonyms: N-BENZYL-2 3-DIBROMOMALEIMIDE 97;1-benzyl-3,4-dibromo-pyrrole-2,5-dione;N-Benzyl-2,3-dibromomaleimide 97%;1-benzyl-3,4-dibromo-1H-pyrrole-2,5-dione
• CAS NO: 91026-00-5
• Molecular Formula: C₁₁H₇Br₂NO₂
• Molecular Weight: 344.99
• Mol File: 91026-00-5.mol
• Article Data: 13

Chemical Properties

• Melting Point: 117-120 °C(lit.)
• Appearance: /
• CAS DataBase Reference: N-BENZYL-2 3-DIBROMOMALEIMIDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYL-2 3-DIBROMOMALEIMIDE 97(91026-00-5)
• EPA Substance Registry System: N-BENZYL-2 3-DIBROMOMALEIMIDE 97(91026-00-5)

Safety Data

• Hazard Codes: C
• Statements: 34-43
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 1759 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 91026-00-5(Hazardous Substances Data)

Usage

Description

N-BENZYL-2 3-DIBROMOMALEIMIDE 97 is a chemical compound that serves as a key intermediate in the synthesis of various maleimide-based dyes. These dyes are known for their fluorescence quenching properties, making them valuable in research and analytical applications.

Uses

Used in Fluorescence Quenching Applications:
N-BENZYL-2 3-DIBROMOMALEIMIDE 97 is used as a precursor in the synthesis of maleimide-based dyes for fluorescence quenching. These dyes are employed in various research and analytical applications, where they can effectively suppress fluorescence signals, allowing for more accurate measurements and analyses.
Used in Synthesis of Maleimide-based Dyes:
N-BENZYL-2 3-DIBROMOMALEIMIDE 97 is used as a starting material in the synthesis of several maleimide-based dyes, including:
1. 2,3-bis(3-indolyl)-N-benzylmaleimide
2. 2,3-bis(2′-methyl-3-indolyl)-N-benzylmaleimide
3. 2,3-bis(2-pyrrolyl)-N-benzylmaleimide
4. 2-aryl-N-benzyl-3-bromomaleimides via Suzuki cross-coupling reaction with aryl boronic acid
These dyes are specifically designed for fluorescence quenching, making them useful in a variety of scientific and industrial applications where the suppression of fluorescence is required.

Upstream product

• 108-31-6 maleic anhydride 
• 100-46-9 benzylamine 
• 1442447-48-4 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester 
• 1631-26-1 1-benzyl-1H-pyrrole-2,5-dione 
• 1122-10-7 2,3-dibromomaleimide 
• 100-51-6 benzyl alcohol 
• 1122-12-9 2,3-dibromomaleic anhydride 
• 608-37-7 dibromomaleic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 894428-75-2 N-benzyl-3-bromo-4-[1-(tert-butoxycarbonyl)-2-methyl-1H-indol-3-yl]maleimide 
• 947407-98-9 N-benzyl-4-(2,5-dimethylthiophen-3-yl)-3-(2-methyl-1H-indol-3-yl)maleimide 
• 894428-79-6 N-benzyl-3-[1-(tert-butoxycarbonyl)-2-methyl-1H-indol-3-yl]-4-(2,5-dimethylthiophen-3-yl)maleimide 
• 91026-01-6 2,3-bis(1H-indol-3-yl)-N-benzylmaleimide 
• 1258503-56-8 1-benzyl-3,4-di(naphthalene-2-yl)-1H-pyrrole-2,5-dione 
• 1258505-51-9 1-benzyl-3,4-di(naphthalen-1-yl)-1H-pyrrole-2,5-dione 
• 1258503-57-9 C₄₃H₂₅NO₂ 
• 75255-81-1 1-benzyl-3,4-diphenyl-1H-pyrrole-2,5-dione 
• 1429862-78-1 1-benzyl-3,4-di-o-tolyl-1H-pyrrole-2,5-dione 
• 1429862-72-5 1-benzyl-3-bromo-4-(o-tolyl)-1H-pyrrole-2,5-dione 
• 1429862-79-2 1-benzyl-3,4-bis(2-ethylphenyl)-1H-pyrrole-2,5-dione 
• 1429862-73-6 1-benzyl-3-bromo-4-(2-ethylphenyl)-1H-pyrrole-2,5-dione 
• 1429862-74-7 1-benzyl-3-bromo-4-(2,3-dimethylphenyl)-1H-pyrrole-2,5-dione 
• 1429862-80-5 1-benzyl-3,4-bis(2,3-dimethylphenyl)-1H-pyrrole-2,5-dione 

Relevant articles and documents

Electrochemical synthesis method of 3,4-dibromomalayimide

The present invention relates to the field of organic synthesis technology, in particular to a 3,4-dibromo maleimide electrochemical synthesis method, maleimide as the starting material, to inexpensive, safe and readily available bromide as a bromine sour

Scalable preparation of stable and reusable silica supported palladium nanoparticles as catalysts for N-alkylation of amines with alcohols

The development of nanoparticles-based heterogeneous catalysts continues to be of scientific and industrial interest for the advancement of sustainable chemical processes. Notably, up-scaling the production of catalysts to sustain unique structural features, activities and selectivities is highly important and remains challenging. Herein, we report the expedient synthesis of Pd-nanoparticles as amination catalysts by the reduction of simple palladium salt on commercial silica using molecular hydrogen. The resulting Pd-nanoparticles constitute stable and reusable catalysts for the synthesis of various N-alkyl amines using borrowing hydrogen technology without the use of any base or additive. By applying this Pd-based catalyst, functionalized and structurally diverse N-alkylated amines as well as some selected drug molecules were synthesized in good to excellent yields. Practical and synthetic utility of this Pd-based amination protocol has been demonstrated by upscaling catalyst preparation and amination reactions to several grams-scales as well as recycling of catalyst. Noteworthy, this Pd-catalyst preparation has been up-scaled to kilogram scale and catalysts prepared in both small (1 g) and large-scale (kg) exhibited similar structural features and activity.

Maleimide-based acyclic enediyne for efficient DNA-cleavage and tumor cell suppression

A pH-sensitive acyclic enediyne (1) was synthesized for efficient DNA-cleavage and tumor cell suppression. Unlike other acyclic enediynes, this novel enediyne transforms into a highly reactive enediyne (2) in an acidic environment only, which undergoes Be