910480-83-0

Basic information

• Product Name: 4-cyclohexyl-5-pyridin-2-yl-1H-pyrrole-2-carbaldehyde
• Synonyms: 4-cyclohexyl-5-pyridin-2-yl-1H-pyrrole-2-carbaldehyde
• CAS NO: 910480-83-0
• Molecular Weight: 254.332
• Mol File: 910480-83-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyclohexyl-5-pyridin-2-yl-1H-pyrrole-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyclohexyl-5-pyridin-2-yl-1H-pyrrole-2-carbaldehyde(910480-83-0)
• EPA Substance Registry System: 4-cyclohexyl-5-pyridin-2-yl-1H-pyrrole-2-carbaldehyde(910480-83-0)

Safety Data

• Hazardous Substances Data: 910480-83-0(Hazardous Substances Data)

Upstream product

• 910480-82-9 2-(3-cyclohexyl-1H-pyrrol-2-yl)-pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 23860-35-7 cyclohexylacetic acid chloride 
• 149108-75-8 2-cyclohexyl-1-(pyridin-2-yl)ethan-1-one 
• 134560-43-3 2-cyclohexyl-N-methoxy-N-methylacetamide 
• 5292-21-7 Cyclohexylacetic acid 
• 918936-53-5 2-cyclohexyl-1-pyridin-2-yl-pent-4-en-1-one 
• 910480-81-8 3-cyclohexyl-4-oxo-4-pyridin-2-yl-butyraldehyde 

Relevant articles and documents

Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds

Benzimidazole-based allosteric inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified to a variety of topologically related scaffolds. Replacement of the polar benzimidazole core by lipophilic indoles led to inhibitors with improved potency in the cell-based subgenomic HCV replicon system. Transposing the indole scaffold into a previously described series of benzimidazole-tryptophan amides generated the most potent inhibitors of HCV RNA replication in cell culture reported to date in this series (EC50 ～ 50 nM).