910575-83-6

Basic information

• Product Name: (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid
• Synonyms: (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid
• CAS NO: 910575-83-6
• Molecular Weight: 263.216
• Mol File: 910575-83-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid(910575-83-6)
• EPA Substance Registry System: (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid(910575-83-6)

Safety Data

• Hazardous Substances Data: 910575-83-6(Hazardous Substances Data)

Upstream product

• 910575-82-5 3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-oxo-propionic acid 
• 92891-23-1 2-nitro-3-trifluoromethyl-toluene 
• 88301-98-8 2-methyl-6-(trifluoromethyl)aniline 
• 864539-96-8 4-bromo-2-methyl-6-(trifluoromethyl)aniline 

Downstream Products

• 910575-84-7 (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid methyl ester 
• 910575-85-8 4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidine-1-carboxylic acid (R)-2-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-1-methoxycarbonyl-ethyl ester 
• 910575-86-9 4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidine-1-carboxylic acid (R)-2-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-1-carboxy-ethyl ester 

Relevant articles and documents

CGRP ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS

The invention relates to CGRP antagonists of general formula (I) in which: R1, R2, R3, R4 and X are defined as in Claim 1, to their tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures and salts as well as the hydrates of the salts, in particular, their physiologically compatible salts with inorganic or organic acids and bases, and those compounds of general formula (I) in which one or more hydrogen atoms are replaced by deuterium. The invention also relates to medicaments containing these compounds, the use thereof, and to methods for producing them.