910867-13-9

Basic information

• Product Name: (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester
• Synonyms: (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester
• CAS NO: 910867-13-9
• Molecular Weight: 535.637
• Mol File: 910867-13-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester(910867-13-9)
• EPA Substance Registry System: (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(hydroxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester(910867-13-9)

Safety Data

• Hazardous Substances Data: 910867-13-9(Hazardous Substances Data)

Upstream product

• 910867-12-8 (3S)-5-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-hydroxy-(4E)pentenoic acid methyl ester 
• 540-88-5 acetic acid tert-butyl ester 
• 1024024-29-0 (5S)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-5-(tetrahydropyranyloxy)-3-oxo-(6E)-heptenoic acid tert-butyl ester 
• 925421-79-0 tert-butyl (5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-yl)-5-(tert-butyldimethylsilyloxy)-3-oxo-hept-6-enoate 

Downstream Products

• 355806-00-7 rosuvastatin tert-butyl ester 

Relevant articles and documents

PROCESS FOR PREPARING ROSUVASTATIN CALCIUM

The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.

PROCESS FOR THE SYNTHESIS OF ROSUVASTATIN CALCIUM

Present invention represents process for the preparation of HMG-CoA reductsase inhibitors, in particular rosuvastatin calcium introducing L-malic acid as the source of chirality for the side chain

PROCESS FOR PREPARATION OF ROSUVASTATIN

The invention relates to commercially viable process for the preparation of Rosuvastatin by an early introduction of the correct absolute stereochemistry at C-5 (S) of Rosuvastatin side chain followed by regioselective chain extension using novel side chain building blocks. It is yet another object of the invention is to provide novel intermediates that may be used for the preparation of Rosuvastatin. Formula (I).