911208-73-6 Usage
Description
3-(Hexadecyloxy)propyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonat, also known as Tenofovir Exalidex, is a prodrug of nucleoside analog with a complex chemical structure. It is characterized by the presence of a hexadecyloxypropyl group, a chiral center with an R-configuration, and a phosphonate group. 3-(Hexadecyloxy)propyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonat has potential applications in the pharmaceutical industry due to its unique properties and interactions with biological systems.
Uses
Used in Pharmaceutical Industry:
3-(Hexadecyloxy)propyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonat is used as a prodrug for the treatment of hepatitis B virus. It is designed to be converted into its active form within the body, providing a targeted approach to treating the virus and minimizing side effects on healthy cells.
Used in Antiviral Therapy:
In the field of antiviral therapy, 3-(Hexadecyloxy)propyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonat serves as a nucleoside analog, which can inhibit the replication of hepatitis B virus. By integrating into the viral genome during replication, it disrupts the normal functioning of the virus and prevents its spread.
Used in Drug Development:
3-(Hexadecyloxy)propyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonat is also used in drug development for the creation of new antiviral agents. Its unique structure and properties make it a valuable starting point for the design of novel compounds with improved efficacy and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 911208-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,1,2,0 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 911208-73:
(8*9)+(7*1)+(6*1)+(5*2)+(4*0)+(3*8)+(2*7)+(1*3)=136
136 % 10 = 6
So 911208-73-6 is a valid CAS Registry Number.
911208-73-6Relevant articles and documents
Novel antiviral nucleoside reverse transcriptase inhibitor
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Paragraph 0311; 0314; 0319; 0320, (2019/04/06)
The invention relates to a novel antiviral nucleoside reverse transcriptase inhibitor compound, a pharmaceutical composition comprising the same and preparation and application thereof. Particularly,the invention discloses a condensed pyrimidine compound
Nucleoside phosphoramidate type compound with HBV/HIV resistance activity and salt and application of nucleoside phosphoramidate type compound
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Paragraph 0070, (2017/08/28)
The invention relates to a nucleoside phosphoramidate type compound with HBV/HIV resistance activity, an isomer of the nucleoside phosphoramidate type compound, pharmaceutically-acceptable salt of the nucleoside phosphoramidate type compound, a solvate or crystal of the nucleoside phosphoramidate type compound, a medicine composition of the nucleoside phosphoramidate type compound, and application of the nucleoside phosphoramidate type compound. According to related novel non-cyclic nucleoside phosphoramidate, on the phosphoramidate part, amino acid is D-amino-acid. D-amino-acid ester is introduced in the prodrug, and a new non-cyclic nucleotide amide compound which has higher chemical stability, higher lipid solubility and higher virus inhibition activity is expected to be obtained. By means of the creative design, the virus resistance activity of medicine is improved, solubility and pharmacokinetics characteristics of the medicine are improved, the concentration ratio in tissue cells and plasma is increased, and therefore the curative effect, safety and tolerance of the medicine can be improved, and very good clinical application prospects are achieved.
