911228-76-7

Basic information

• Product Name: N,N-diethyl-3-hydroxy-4-iodobenzaMide
• Synonyms: N,N-diethyl-3-hydroxy-4-iodobenzaMide
• CAS NO: 911228-76-7
• Molecular Formula: C₁₁H₁₄INO₂
• Molecular Weight: 319.13883
• Mol File: 911228-76-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 378.531 °C at 760 mmHg
• Flash Point: 182.729 °C
• Appearance: /
• Density: 1.61 g/cm³
• CAS DataBase Reference: N,N-diethyl-3-hydroxy-4-iodobenzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-3-hydroxy-4-iodobenzaMide(911228-76-7)
• EPA Substance Registry System: N,N-diethyl-3-hydroxy-4-iodobenzaMide(911228-76-7)

Safety Data

• Hazardous Substances Data: 911228-76-7(Hazardous Substances Data)

Upstream product

• 58123-77-6 3-hydroxy-4-iodobenzoic acid 
• 109-89-7 diethylamine 

Downstream Products

• 1309682-63-0 Ν,Ν-diethyl-4-iodo-3-(2,2,2-trifluoroethoxy)benzamide 
• 1309682-65-2 3-(cyclopropylmethoxy)-N,N-diethyl-4-iodobenzamide 
• 887412-13-7 N,N-diethyl-4-iodo-3-(2-methoxyethoxy)benzamide 
• 1309682-64-1 N,N-diethyl-4-iodo-3-propoxybenzamide 
• 1403330-58-4 N,N-diethyl-4-{[6-(4-{[(4-fluorophenyl)acetyl]amino}phenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino}-3-(2-methoxyethoxy)benzamide 
• 1403330-57-3 N,N-diethyl-4-{[6-(4-{[(4-fluorophenyl)acetyl]amino}phenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino}-3-isopropoxybenzamide 
• 1403330-56-2 3-(cyclopropylmethoxy)-N,N-diethyl-4-{[6-(4-{[(4-fluorophenyl)acetyl]amino}phenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino}benzamide 
• 1403330-55-1 N,N-diethyl-4-{[6-(4-{[(4-fluorophenyl)acetyl]amino}phenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino}-3-propoxybenzamide 
• 1403330-54-0 N,N-diethyl-4-{[6-(4-{[(4-fluorophenyl)acetyl]amino}phenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino}-3-(2,2,2-trifluoroethoxy)benzamide 
• 1309681-07-9 N,N-diethyl-3-(2,2,2-trifluoroethoxy)-4-[(6-{4-[(2,2,2-trifluoroethyl)-carbamoyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)amino]benzamide 

Relevant articles and documents

SUBSTITUTED TRIAZOLOPYRIDINES

The present invention relates to substituted triazolopyridine compounds of general formula (I); in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.

SUBSTITUTED TRIAZOLOPYRIDINES

The present invention relates to substituted triazolopyridine compounds of general formula (I) : in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease such as tumours and proliferative diseases, as well as to intermediate compounds useful in the preparation of said compounds.

TRIAZOLOPYRIDINE DERIVATIVES

The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of proliferative diseases, as well as to intermediate compounds useful in the preparation of said compounds.