911303-02-1

Basic information

• Product Name: 3-[(4-methylphenylsulfonyl)(phenyl)methyl]-1H-indole
• Synonyms: 3-[(4-methylphenylsulfonyl)(phenyl)methyl]-1H-indole
• CAS NO: 911303-02-1
• Molecular Weight: 361.464
• Mol File: 911303-02-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-[(4-methylphenylsulfonyl)(phenyl)methyl]-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(4-methylphenylsulfonyl)(phenyl)methyl]-1H-indole(911303-02-1)
• EPA Substance Registry System: 3-[(4-methylphenylsulfonyl)(phenyl)methyl]-1H-indole(911303-02-1)

Safety Data

• Hazardous Substances Data: 911303-02-1(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 3696-52-4 Ethyl-N-<α-(p-toluolsulfonyl)-benzyl>-carbamat 
• 271600-36-3 N-[phenyl(toluene-4-sulfonyl)methyl]tert-butoxycarboxyamide 
• 372199-85-4 [phenyl-(toluene-4-sulfonyl)-methyl]-carbamic acid benzyl ester 
• 536-57-2 p-toluene sulfinic acid 
• 100-52-7 benzaldehyde 
• 35173-74-1 3,3'-bis-indolyl(phenyl)methane 
• 824-79-3 sodium 4-methylbenzenesulfinate 

Downstream Products

• 16886-10-5 3-benzyl-1H-indole 
• 1099592-70-7 C₂₀H₂₁NO 
• 1208321-06-5 tert-butyl 2-((1H-indol-3-yl)(phenyl)methyl)-1,4-dimethyl-3,6-dioxopiperazine-2-carboxylate 
• 1221525-93-4 (2S,3S)-tert-butyl-2-(diphenylmethyleneamino)-3-(1H-indol-3-yl)-3-phenylpropanoate 
• 1443532-51-1 3-[(R)-2-fluoro-1-phenyl-2,2-bis(phenylsulfonyl)ethyl]-1H-indole 
• 57582-18-0 3-(1-phenylpropyl)-1H-indole 
• 1443383-03-6 C₂₅H₁₉NO 

Relevant articles and documents

Copper-Catalyzed Addition of Grignard Reagents to in situ Generated Indole-Derived Vinylogous Imines

Chiral indole derivatives are ubiquitous motifs in pharmaceuticals and alkaloids. Herein, the first protocol for catalytic asymmetric conjugate addition of Grignard reagents to various sulfonyl indoles, offering a straightforward approach for the synthesis of chiral 3-sec-alkyl-substituted indoles in high yields and enantiomeric ratios is presented. This methodology makes use of a chiral catalyst based on copper phosphoramidite complexes and in situ formation of vinylogous imine intermediates.

Highly enantioselective monofluoromethylation of C2-arylindoles using FBSM under chiral phase-transfer catalysis

The highly enantioselective addition of 1-fluoro-1,1-bis(phenylsulfonyl) methane (FBSM) to vinylogous imines generated in situ from 2-aryl-3-(1- arylsulfonylmethyl)indoles was achieved using chiral ammonium salts derived from cinchona alkaloids. One-pot c

InBr3: A versatile catalyst for the different types of Friedel-Crafts reactions

(Chemical Equation Presented) Mild and efficient InBr3-catalyzed Friedel-Crafts alkylation of heteroaromatic or electron-rich aromatic compounds with α-amido sulfones at room temperature in CH2Cl2 has been developed. The p