911418-15-0

Basic information

• Product Name: tert-butyl 5-(2-[(3-phenyl)phenyl]-6-hydroxy-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate
• Synonyms: tert-butyl 5-(2-[(3-phenyl)phenyl]-6-hydroxy-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate
• CAS NO: 911418-15-0
• Molecular Weight: 559.624
• Mol File: 911418-15-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 5-(2-[(3-phenyl)phenyl]-6-hydroxy-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5-(2-[(3-phenyl)phenyl]-6-hydroxy-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate(911418-15-0)
• EPA Substance Registry System: tert-butyl 5-(2-[(3-phenyl)phenyl]-6-hydroxy-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate(911418-15-0)

Safety Data

• Hazardous Substances Data: 911418-15-0(Hazardous Substances Data)

Upstream product

• 29568-78-3 4,5-dimethoxy-2-nitrobenzoyl chloride 
• 4959-60-8 4,5-dimethoxy-2-nitrobenzamide 
• 4998-07-6 4,5-dimethoxy-2-nitro-benzoic acid 
• 5004-88-6 4,5-dimethoxyanthranilamide 
• 911418-13-8 4-chloro-2-[(3-phenyl)phenyl]-7-methoxyquinazolin-6-yl acetate 
• 911418-12-7 2-[(3-phenyl)phenyl]-7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate 
• 911418-10-5 2-[(3-phenyl)phenyl]-6,7-dimethoxyquinazolin-4(3H)-one 

Downstream Products

• 911418-21-8 tert-butyl 5-(6-(2-chloroethoxy)-2-[(3-phenyl)phenyl]-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911418-17-2 2-(4-(1H-indazol-5-ylamino)-2-[(3-phenyl)phenyl]-7-methoxyquinazolin-6-yloxy)acetic acid 
• 911418-25-2 tert-butyl 5-(2-[(3-phenyl)phenyl]-7-methoxy-6-(2-(4-methylpiperazin-1-yl)ethoxy)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911418-16-1 tert-butyl 5-(6-(2-tert-butoxy-2-oxoethoxy)-2-[(3-phenyl)phenyl]-7-methoxyquinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911418-19-4 tert-butyl 5-(2-[3-(phenyl)phenyl]-7-methoxy-6-(2-methoxyethoxy)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 

Relevant articles and documents

PHARMACOKINETICALLY IMPROVED COMPOUNDS

The present invention relates to inhibitors of ROCKl and R0CK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCKl and or R0CK2 that are useful for the treatment of disease.