911437-83-7

Basic information

• Product Name: 7-((R)-2-Benzyloxy-1-hydroxymethyl-ethylcarbamoyl)-heptanoic acid methyl ester
• Synonyms: 7-((R)-2-Benzyloxy-1-hydroxymethyl-ethylcarbamoyl)-heptanoic acid methyl ester
• CAS NO: 911437-83-7
• Molecular Weight: 351.443
• Mol File: 911437-83-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-((R)-2-Benzyloxy-1-hydroxymethyl-ethylcarbamoyl)-heptanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-((R)-2-Benzyloxy-1-hydroxymethyl-ethylcarbamoyl)-heptanoic acid methyl ester(911437-83-7)
• EPA Substance Registry System: 7-((R)-2-Benzyloxy-1-hydroxymethyl-ethylcarbamoyl)-heptanoic acid methyl ester(911437-83-7)

Safety Data

• Hazardous Substances Data: 911437-83-7(Hazardous Substances Data)

Upstream product

• 3946-32-5 suberic acid monomethyl ester 
• 911437-82-6 7-[1-benzyloxymethyl-2-(tert-butyl-diphenyl-silanyloxy)-ethylcarbamoyl]-heptanoic acid methyl ester 

Downstream Products

• 911437-84-8 7-((S)-4-Benzyloxymethyl-4,5-dihydro-oxazol-2-yl)-heptanoic acid methyl ester 
• 911437-85-9 7-((S)-4-Benzyloxymethyl-4,5-dihydro-oxazol-2-yl)-heptanoic acid phenylamide 

Relevant articles and documents

Exploring alternative Zn-binding groups in the design of HDAC inhibitors: Squaric acid, N-hydroxyurea, and oxazoline analogues of SAHA

Analogues of suberoylanilide hydroxamic acid (SAHA) were prepared by replacing the Zn-binding group with squaric acid, N-hydroxyurea, and 4-hydroxymethyl oxazoline units, also varying the length of the aliphatic chain. No inhibitory activity on HDAC was observed below 1.0 μM and no cytotoxic activity on different tumor cell lines was seen below 20.0 μM.