912368-73-1 Usage
General Description
1-N-Boc-3-(S)-Methylamino-piperidine is a chemical compound with the molecular formula C13H25NO2 and a molecular weight of 239.34 g/mol. It is a derivative of piperidine and contains a tert-butoxycarbonyl (Boc) protective group at the nitrogen atom and a methylamino group at the 3-position in the piperidine ring. 1-N-Boc-3-(S)-Methylamino-piperidine is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. It is also used as a precursor in the synthesis of other complex organic molecules. The Boc protective group helps to protect the amino group from unwanted reactions during the synthesis process, while the methylamino group can participate in various chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 912368-73-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,3,6 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 912368-73:
(8*9)+(7*1)+(6*2)+(5*3)+(4*6)+(3*8)+(2*7)+(1*3)=171
171 % 10 = 1
So 912368-73-1 is a valid CAS Registry Number.
912368-73-1Relevant articles and documents
Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity
Arita, Tsuyoshi,Asano, Masayoshi,Kubota, Kazufumi,Domon, Yuki,Machinaga, Nobuo,Shimada, Kousei
supporting information, (2019/11/11)
We synthesized derivatives of a natural alkaloid, conolidine, and evaluated these derivatives in the acetic acid-induced writhing test and formalin test in ddY mice after oral administration. As a result, we identified (5S)-6-methyl-1,3,4,5,6,8-hexahydro-7H-2,5-methano[1,5]diazonino[7,8-b]indol-7-one sulfate salt, 15a (DS54360155), with a unique and original bicyclic skeleton, as an analgesic more potent than conolidine. Moreover, 15a did not exhibit mu-opioid receptor agonist activity.
BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE
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Page/Page column 99, (2018/02/03)
Compounds of formula (I): wherein Ra and Rb are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful as alpha2C antagonists.
