91248-14-5

Basic information

• Product Name: 2-(3,4,5-trimethoxyphenyl)acetamide
• CAS NO: 91248-14-5
• Molecular Formula: C₁₁H₁₅NO₄
• Molecular Weight: 225.2411
• Mol File: 91248-14-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 401.5°C at 760 mmHg
• Flash Point: 203.5°C
• Density: 1.154g/cm³
• Vapor Pressure: 1.17E-06mmHg at 25°C
• Refractive Index: 1.521
• CAS DataBase Reference: 2-(3,4,5-trimethoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4,5-trimethoxyphenyl)acetamide(91248-14-5)
• EPA Substance Registry System: 2-(3,4,5-trimethoxyphenyl)acetamide(91248-14-5)

Safety Data

• Hazardous Substances Data: 91248-14-5(Hazardous Substances Data)

Usage

Chemical structure

2-(3,4,5-trimethoxyphenyl)acetamide consists of a phenyl ring with three methoxy groups attached to it and an acetamide functional group.

Usage

It is commonly used in organic synthesis and pharmaceutical research.

Biological activity

The presence of the methoxy groups can enhance the compound's biological activity, making it useful in the development of new drugs.

Potential applications

2-(3,4,5-trimethoxyphenyl)acetamide may have potential applications in the treatment of various diseases due to its structural features and pharmacological properties.

Building block

It can be used as a building block in the synthesis of more complex organic molecules.

Upstream product

• 951-82-6 3,4,5-trimethoxyphenyl acetic acid 
• 2989-06-2 methyl 2-(3,4,5-trimethoxyphenyl)acetate 
• 39053-78-6 3,4,5-trimethoxyphenylacetyl chloride 
• 7702-09-2 2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone 
• 13338-63-1 2-(3,4,5-trimethoxyphenyl)acetonitrile 

Downstream Products

• 863223-52-3 3-(1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione 
• 1215293-96-1 3-(5-fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione 
• 1312545-37-1 3-(1-{3-[(tert.-butoxycarbonyl)amino]propyl}-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-maleinimide 
• 1312545-35-9 3-(1-{2-[(tert.-butoxycarbonyl)amino]ethyl}-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-maleinimide 
• 1312545-23-5 3-(4-azaindol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrol-2,5-dione 
• 1215293-98-3 3-(5-iodo-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione 
• 100389-03-5 1-chloro-3-(3,4,5-trimethoxy-phenyl)-acetone 

Relevant articles and documents

3-(5-FLUOROINDOLYL)-4-ARYLMALEIMIDE COMPOUNDS AND THEIR USE IN TUMOR TREATMENT

The present invention relates to 3-(5-fluoroindolyl)-4-arylmaleimide compounds, pharmaceutical compositions containing them. The compounds of the present invention have antineoplastic activity. They can therefore be used for the treatment or prevention of

Novel 3-azaindolyl-4-arylmaleimides exhibiting potent antiangiogenic efficacy, protein kinase inhibition, and antiproliferative activity

Tumor growth and metastasis are highly associated with the overexpression of protein kinases (PKs) regulating cell growth, apoptosis resistance, and prolonged cell survival. This study describes novel azaindolyl-maleimides with significant inhibition of PKs, such as VEGFR, FLT-3, and GSK-3β which are related to carcinogenesis. Furthermore, these compounds exhibit high kinase selectivity and potent inhibition of angiogenesis and cell proliferation, offering versatile options in cancer treatment strategies.

Synthesis of derivatives of [I-131] phenylalkylamines for brain mapping

The synthesis and spectral properties of new radioiodinated phenylalkylamines like 2-[131I]-iodo-4,5-dimethoxyphenethylamine, 2- [131I]-iodo-4,5-dimethoxy-N,N-dimethylphenethylamine 2-[131I]- iodophenethylamine, 2-[131I]-iodo-N,N-dimethylphenethylamine, 2-[131I]- iodo-3,4,5-trimethoxy-phenethylamine (mescaline) are described for the first time. These compounds are of biological importance and can be used for brain mapping with SPECT technology.