912641-81-7

Basic information

• Product Name: tert-butyl 2-(2-cyaNAbenzo[d]thiazol-6-ylaMiNA)-2-oxoethylcarbaMate
• Synonyms: tert-butyl 2-(2-cyaNAbenzo[d]thiazol-6-ylaMiNA)-2-oxoethylcarbaMate
• CAS NO: 912641-81-7
• Molecular Formula: C15H16N4O3S
• Molecular Weight: 332.38
• Mol File: 912641-81-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 2-(2-cyaNAbenzo[d]thiazol-6-ylaMiNA)-2-oxoethylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(2-cyaNAbenzo[d]thiazol-6-ylaMiNA)-2-oxoethylcarbaMate(912641-81-7)
• EPA Substance Registry System: tert-butyl 2-(2-cyaNAbenzo[d]thiazol-6-ylaMiNA)-2-oxoethylcarbaMate(912641-81-7)

Safety Data

• Hazardous Substances Data: 912641-81-7(Hazardous Substances Data)

Upstream product

• 7724-12-1 2-cyano-6-aminobenzothiazole 
• 66866-43-1 N-(t-butoxycarbonyl)glycyl i-butyl carbonate 
• 4530-20-5 BOC-glycine 
• 2406-90-8 2-chlorobenzothiazol-6-ylamine 
• 2407-11-6 2-chloro-6-nitrobenzothiazole 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 

Downstream Products

• 1289513-02-5 tert-butyl 1-(2-(2-cyanobenzo[d]thiazol-6-ylamino)-2-oxoethylamino)-1-oxo-3-(tritylthio)propan-2-ylcarbamate 

Relevant articles and documents

CROSSLINKED MATERIALS

The present application describes to the synthesis, formulation and uses of crosslinkable entities and crosslinked materials.

Sequence-specific 2-cyanobenzothiazole ligation

The use of small, natural chemical reporters in conjunction with catalyst-free bioorthogonal reactions will greatly streamline protein labeling in a cellular environment with minimum perturbation to their function. Here we report the discovery of a 2-cyan

Controlling intracellular macrocyclization for the imaging of protease activity

(Figure Presented) Reporters on the ground: An intramolecular macrocyclization reaction took place highly efficiently in live cells under the control of a specific enzyme and reduction by glutathione (GSH; see picture). Macrocyclic products (represented as blue rings) synthesized in cells self-assembled into nanoparticles aggregated and retained at the site near the enzyme location to report local proteolytic activity in live cells.