912849-73-1 Usage
Description
O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)NONAETHYLENE GLYCOL, also known as Azido-PEG10-amine, is a bifunctional crosslinker with 10 PEG units. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO, and BCN moieties to form triazole groups. The amine group can react with carboxylic acids, activated NHS esters, and other carbonyl compounds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous solutions.
Uses
Used in Intramolecular Linker Construction:
O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)NONAETHYLENE GLYCOL is used as an intramolecular linker for constructing complex molecular structures and facilitating specific interactions between different parts of a molecule.
Used in Synthesis of PEGylated TLR7 Ligands:
O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)NONAETHYLENE GLYCOL is used as a key component in the synthesis of potent PEGylated toll-like receptor 7 (TLR7) ligands. This application aims to improve the solubility and modulate protein binding, enhancing the overall effectiveness of the ligands in immune response modulation and therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 912849-73-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,8,4 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 912849-73:
(8*9)+(7*1)+(6*2)+(5*8)+(4*4)+(3*9)+(2*7)+(1*3)=191
191 % 10 = 1
So 912849-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H46N4O10/c23-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-25-26-24/h1-23H2
