91292-73-8

Basic information

• Product Name: L-Alanine, N-[(4-chlorophenyl)methylene]-, methyl ester
• CAS NO: 91292-73-8
• Molecular Formula: C11H12ClNO2
• Molecular Weight: 225.675
• Mol File: 91292-73-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: L-Alanine, N-[(4-chlorophenyl)methylene]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, N-[(4-chlorophenyl)methylene]-, methyl ester(91292-73-8)
• EPA Substance Registry System: L-Alanine, N-[(4-chlorophenyl)methylene]-, methyl ester(91292-73-8)

Safety Data

• Hazardous Substances Data: 91292-73-8(Hazardous Substances Data)

Upstream product

• 2491-20-5 L-alanine methyl ester hydrochloride 
• 104-88-1 4-chlorobenzaldehyde 
• 7625-53-8 rac-Ala-OMe 
• 10065-72-2 L-Alanine methyl ester 
• 13515-97-4 methyl 2-aminopropanoate monohydrochloride 

Downstream Products

• 111396-05-5 5-(4-Chloro-phenyl)-4-formyl-2,3-dimethyl-pyrrolidine-2-carboxylic acid methyl ester 
• 111395-98-3 4-Benzoyl-5-(4-chloro-phenyl)-3-(4-methoxy-phenyl)-2-methyl-pyrrolidine-2-carboxylic acid methyl ester 
• 404927-60-2 C₂₂H₃₄ClNO₃Si 
• 28385-45-7 L-α-methylphenylalanine methyl ester 
• 38574-55-9 (R)-(-)-methyl 2-amino-2-methyl-3-phenylpropionate 
• 1138343-09-5 C₂₀H₂₄N₂O₃ 
• 4507-41-9 2-amino-2-phenyl propanoate de methyle 
• 111396-07-7 5-(4-Chloro-phenyl)-2,4-dimethyl-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 113891-89-7 2-{[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-2-methyl-pentanedioic acid dimethyl ester 
• 113973-70-9 2-{[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-4-cyano-2-methyl-butyric acid methyl ester 
• 111396-00-0 4-Benzoyl-5-(4-chloro-phenyl)-2-methyl-3-phenyl-pyrrolidine-2-carboxylic acid methyl ester 
• 15080-35-0 α-Methyl p-chlorophenylalanine 

Relevant articles and documents

Enantioenriched α-substituted glutamates/pyroglutamates via enantioselective cyclopropenimine-catalyzed Michael addition of amino ester imines

A procedure for the enantioselective synthesis of α-substituted glutamates and pyroglutamates via a cyclopropenimine-catalyzed Michael addition of amino ester imines is described. Enantioselectivities of up to 94% have been achieved, and a variety of functional groups were found to be compatible. The impact of the catalyst structure and imine substitution is discussed. Compared to other methods, this protocol allows for a broader and more enantioselective access to pyroglutamate derivatives.

Synthesis of novel multi-functionalized pyrrolidines by [3 + 2] dipolar cycloaddition of azomethine ylides and vinyl ketones

Abstract: An efficient and easy synthetic route to substituted pyrrolidine derivatives has been established through [3 + 2] dipolar cycloaddition of vinyl ketones and azomethine ylides. The reactions proceed smoothly, under mild conditions, affording mode

Ag2CO3/CA-AA-amidphos multifunctional catalysis in the enantioselective 1,3-dipolar cycloaddition of azomethine ylides

The new Ag2CO3/CA-AA-amidphos complexes have been demonstrated as highly efficient multifunctional catalysts in the asymmetric 1,3-dipolar cycloaddition of azomethine ylides. Under optimal conditions, highly functionalized endo-4 pyrrolidines were obtained with excellent yields (up to 99% yield) and enantioselectivities (up to 96% ee).