912942-82-6

Basic information

• Product Name: methanesulfonic acid (S)-2-{4-[2,3-dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydro-indol-1-ylmethyl]-phenoxy}ethyl ester
• Synonyms: methanesulfonic acid (S)-2-{4-[2,3-dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydro-indol-1-ylmethyl]-phenoxy}ethyl ester
• CAS NO: 912942-82-6
• Molecular Weight: 614.697
• Mol File: 912942-82-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methanesulfonic acid (S)-2-{4-[2,3-dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydro-indol-1-ylmethyl]-phenoxy}ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: methanesulfonic acid (S)-2-{4-[2,3-dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydro-indol-1-ylmethyl]-phenoxy}ethyl ester(912942-82-6)
• EPA Substance Registry System: methanesulfonic acid (S)-2-{4-[2,3-dioxo-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-2,3-dihydro-indol-1-ylmethyl]-phenoxy}ethyl ester(912942-82-6)

Safety Data

• Hazardous Substances Data: 912942-82-6(Hazardous Substances Data)

Upstream product

• 220509-98-8 5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione 
• 174213-51-5 (S)-tert-butyl 2-(phenoxymethyl)pyrrolidine-1-carboxylate 
• 174213-76-4 (S)-2-(phenoxymethyl)-pyrrolidine 
• 18800-34-5 1-bromo-2-(4'-methylphenoxy)ethane 
• 899818-28-1 1-(2-bromoethoxy)-4-(bromomethyl)benzene 
• 899818-41-8 (S)-1-[4-(2-bromoethoxy)-benzyl]-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione 
• 2386-52-9 silver methanesulfonate 

Downstream Products

• 912942-83-7 <18F>WC-II-89 

Relevant articles and documents

ISATIN ANALOGUES AND USES THEREFOR

Novel isatin analogues, including isatin analogues comprising Michael Acceptors (IMAs) are disclosed. Further disclosed are methods of synthesis of the isatin analogues, and uses of the analogues, including inhibition of caspase-3 and caspase-7, and in vi

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis

A non-peptide-based isatin sulfonamide analog, WC-II-89, was synthesized and its inhibition toward recombinant human caspase-3 and other caspases was determined. This compound showed high potency for inhibiting caspase-3 and -7, and high selectivity again