913563-89-0

Basic information

• Product Name: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(4-chloro-3-trifluoromethylbenzyl)pent-4-enamide
• Synonyms: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(4-chloro-3-trifluoromethylbenzyl)pent-4-enamide
• CAS NO: 913563-89-0
• Molecular Weight: 511.349
• Mol File: 913563-89-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(4-chloro-3-trifluoromethylbenzyl)pent-4-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(4-chloro-3-trifluoromethylbenzyl)pent-4-enamide(913563-89-0)
• EPA Substance Registry System: 2-{[(5-chloro-2-methoxyphenyl)sulfonyl]amino}-N-(4-chloro-3-trifluoromethylbenzyl)pent-4-enamide(913563-89-0)

Safety Data

• Hazardous Substances Data: 913563-89-0(Hazardous Substances Data)

Upstream product

• 885679-07-2 2-([(5-chloro-2-methoxyphenyl)sulfonyl]amino)pent-4-enoic acid 
• 62039-92-3 4-chloro-3-(trifluoromethyl)benzylamine 
• 1069-48-3 rac-allylglycine 
• 22952-32-5 5-chloro-2-methoxybenzenesulfonyl chloride 

Downstream Products

• 913563-91-4 2-{N-[(5-chloro-2-methoxyphenyl)sulfonyl]-N-(2-trifluoromethylallyl)amino}-N-(4-chloro-3-trifluoromethylbenzyl)pent-4-enamide 

Relevant articles and documents

RCM-mediated synthesis of trifluoromethyl-containing nitrogen heterocycles

(Chemical Equation Presented) A ring-closing metathesis mediated pathway to trifluoromethyl-containing piperidines is detailed. This involves the development of a synthetic route to a new (trifluoromethyl)allylating reagent via a Diels-Alder/retro-Diels-Alder strategy, its application in the synthesis of a series of trifluormethyl-substituted diolefin recursors for ring-closing metathesis, and eventually the successful cyclization of these precursor molecules into the corresponding functionalized piperidines.