913836-10-9

Basic information

• Product Name: 3-BORONO-2-METHOXYBENZOIC ACID
• Synonyms: 3-BORONO-2-METHOXYBENZOIC ACID;3-CARBOXY-2-METHOXYPHENYLBORONIC ACID;3-Carboxy-2-methoxybenzeneboronic acid;3-Carboxy-2-methoxybenzeneboronic acid 98%;3-BORONO-2-METHOXYPHENYLBORONIC ACID;2-methoxy-3-carboxylphenylboronic acid;3-Carboxy-2-methoxybenzeneboronicacid98%;Boronic-methoxy carboxyxlic acid
• CAS NO: 913836-10-9
• Molecular Formula: C₈H₉BO₅
• Molecular Weight: 195.96506
• Product Categories: blocks;BoronicAcids
• Mol File: 913836-10-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 152-155℃
• Boiling Point: 456 °C at 760 mmHg
• Flash Point: 229.6 °C
• Appearance: /
• Density: 1.39 g/cm³
• Vapor Pressure: 4.17E-09mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: 2-8°C
• PKA: 4.10±0.10(Predicted)
• CAS DataBase Reference: 3-BORONO-2-METHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BORONO-2-METHOXYBENZOIC ACID(913836-10-9)
• EPA Substance Registry System: 3-BORONO-2-METHOXYBENZOIC ACID(913836-10-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 913836-10-9(Hazardous Substances Data)

Usage

General Description

3-Borono-2-methoxybenzoic acid is a chemical compound with the molecular formula C8H9BO5. It is a boronic acid derivative with a methoxy group and a carboxylic acid group attached to a benzene ring. 3-BORONO-2-METHOXYBENZOIC ACID is used in organic synthesis as a building block for various pharmaceuticals and agrochemicals. The boronic acid group can form reversible covalent bonds with other molecules, making it useful in the development of medicinal drugs and chemical sensors. Its structure and properties make it a versatile and valuable compound in the field of chemical research and drug development.

InChI:InChI=1/C8H9BO5/c1-14-7-5(8(10)11)3-2-4-6(7)9(12)13/h2-4,12-13H,1H3,(H,10,11)

Upstream product

• 124-38-9 carbon dioxide 
• 38603-09-7 2,6-dibromoanisole 

Downstream Products

• 1256337-30-0 [4-[2-(3-tert-butoxycarbonyl-2-methoxy-phenyl)-1-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0(2,6)]dec-4-yl)-ethylcarbamoyl]-benzyl]-triethyl-ammonium bromide 
• 1256336-60-3 [4-[2-(3-tert-butoxycarbonyl-2-methoxy-phenyl)-1-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0(2,6)]dec-4-yl)-ethylcarbamoyl]-benzyl]-pyridinium bromide 
• 1256335-63-3 (1R)-(4-(triethylamino)-methyl)-benzoylamino-(3-carboxy-2-hydroxy)benzyl-methyl boronic acid bromide 
• 1256336-76-1 3-(2-(3-((acetyl-(2-tert-butoxycarbonylamino-ethyl)-amino)-methyl)-benzoylamino)-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0(2,6)]dec-4-yl)-ethyl)-2-methoxy-benzoic acid tert-butyl ester 
• 1256336-56-7 2-methoxy-3-[2-((4-boc-piperazinylmethyl)-benzoylamino)-2-{2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0(2,6)]dec-4-yl}-ethyl]-benzoic acid tert-butyl ester 
• 1256337-23-1 3-[2-[(4-(benzyloxycarbonylamino-imino-methyl)-phenyl)acetylamino]-2-(2,9,9-trimethyl-3,5-doxa-4-bora-tricyclo[6.1.1.0.(2,6)]dec-4-yl)-ethyl]-2-methoxy-benzoic acid tert-butyl ester 
• 1256336-62-5 {4-[2-(3-tert-butoxycarbonyl-2-methoxy-phenyl)-1-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6,1,1,0(2,6)]dec-4-yl)-ethylcarbamoyl]-benzyl}-2-tert-butoxycarbonylamino-ethylamine 
• 1256336-59-0 1-{4-[2-(3-tert-butoxycarbonyl-2-methoxy-phenyl)-1-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0(2,6)]dec-4-yl)-ethyl-carbamoyl]benzyl}piperidine-3-caroxylic acid ethyl ester 
• 1256336-66-9 3-[2-{3-((2-tert-butoxycarbonylamino-ethylamino)-methyl)-benzoylamipo}-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0(2,6)]dec-4-yl)-ethyl]-2-methoxy-benzoic acid tert-butyl ester 
• 1256336-61-4 (1R)-[4-(pyridinium)-methyl]-benzoylamino-(3-carboxy-2-hydroxy)benzyl-methyl boronic acid chloride 
• 1256337-19-5 3-[2-(2-(4-((tert-butoxycarbonylmethyl)-aminomethyl)-phenyl)-acetylamino)-2-(2,9,9-trimethyl-3,5-doxa-4-bora-tricyclo[6.1.1.0.(2,6)]dec-4-yl)-ethyl]-2-methoxy-benzoic acid tert-butyl ester 

Relevant articles and documents

One-pot generation of lithium (lithiophenyl)trialkoxyborates from substituted dihalobenzenes (Hal = Br, I) and their derivatization with electrophiles

The simple one-pot approach to synthetically useful phenyltrialkoxyborates bearing lithium at the phenyl ring has been developed starting with 1,3- and 1,4-diiodobenzene, as well as several activated dibromobenzenes and bromoiodobenzenes. The general sequence of transformations involves halogen-lithium exchange by using nBuLi and subsequent boronation with a trialkylborate. The resulting lithium (halophenyl) trialkoxyborates were then subjected to halogen-lithium exchange in situ with a second equivalent of nBuLi to give dianionic lithium (lithiophenyl)trialkoxyborates. Treatment with selected electrophiles afforded substituted arylboronic acids and/or their pinacol esters as final products in moderate-to-good yields. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.