91420-45-0Relevant articles and documents
AN EFFICIENT FRIEDEL-CRAFTS SYNTHESIS OF 2-ACYLBENZOFURANS
Gill, Melvyn
, p. 621 - 626 (2007/10/02)
2-(Trimethylsilyl)benzofuran, available quantitatively from benzofuran itself, reacts rapidly with primary, secondary, and tertiary aliphatic carboxylic acid chlorides in the presence of titanium(IV) chloride at low temperature to afford the corresponding 2-acylbenzofurans in excellent yields.This approach offers significant synthetic advantage over existing routes to the title compounds.