914300-74-6Relevant articles and documents
Total synthesis of iejimalide A-D and assessment of the remarkable actin-depolymerizing capacity of these polyene macrolides
Fuerstner, Alois,Nevado, Cristina,Waser, Mario,Tremblay, Martin,Chevrier, Carine,Teply, Filip,Aissa, Christophe,Moulin, Emilie,Mueller, Oliver
, p. 9150 - 9161 (2008/02/10)
A concise and convergent total synthesis of the highly cytotoxic marine natural products iejimalide A-D (1-4) is reported, which relies on an effective ring-closing metathesis (RCM) reaction of a cyclization precursor containing no less than 10 double bon