914613-36-8 Usage
Description
2H-2-Ethyl Candesartan Cilexetil, also known as Candesartan Cilexetil EP Impurity F, is a white solid impurity derived from the synthesis of Candesartan Cilexetil, a medication used to treat hypertension and heart failure.
Uses
Used in Pharmaceutical Industry:
2H-2-Ethyl Candesartan Cilexetil is used as a Candesartan Cilexetil impurity for quality control and assurance purposes in the manufacturing process of Candesartan Cilexetil. It helps in monitoring the purity and effectiveness of the final drug product, ensuring the safety and efficacy of the medication for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 914613-36-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,6,1 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 914613-36:
(8*9)+(7*1)+(6*4)+(5*6)+(4*1)+(3*3)+(2*3)+(1*6)=158
158 % 10 = 8
So 914613-36-8 is a valid CAS Registry Number.
914613-36-8Relevant articles and documents
Identification, synthesis and structural determination of some impurities of candesartan cilexetil
Havllcek, Jaroslav,Mandelova, Zuzana,Weisemann, Ruediger,Strelec, Ivo,Placek, Lukas,Radl, Stanislav
experimental part, p. 347 - 362 (2009/06/28)
All principal candesartan cilexetil impurities and/or degradation products were synthesized and identified. The differentiation of N-l and N-2 ethylated candesartan cilexetil derivatives was performed using ID and 2D NMR experiments. The influence of the magnetic field on the resolution and sensitivity of NMR experiments is shown. Selective hydrolysis of these compounds then provided corresponding producrs of hydrolysis of the ethoxy group. Institute of Organic Chemistry and Biochemistry.
