914672-41-6Relevant articles and documents
3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase
Hendricks, Robert T.,Spencer, Stacey R.,Blake, James F.,Fell, Jay B.,Fischer, John P.,Stengel, Peter J.,Leveque, Vincent J.P.,LePogam, Sophie,Rajyaguru, Sonal,Najera, Isabel,Josey, John A.,Swallow, Steven
, p. 410 - 414 (2011/03/18)
Isoquinoline-based non-nucleoside inhibitors of HCV NS5b RNA-dependent RNA-polymerase are described. The synthesis and structure-activity relationships are detailed, along with enzyme and cellular activity.