915302-21-5

Basic information

• Product Name: 2-chloropyrido[3,2-d]pyrimidine
• Synonyms: 2-chloropyrido[3,2-d]pyrimidine
• CAS NO: 915302-21-5
• Molecular Weight: 165.582
• Mol File: 915302-21-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 119-120 °C
• Boiling Point: 263.9±22.0 °C(Predicted)
• Density: 1.437±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-chloropyrido[3,2-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloropyrido[3,2-d]pyrimidine(915302-21-5)
• EPA Substance Registry System: 2-chloropyrido[3,2-d]pyrimidine(915302-21-5)

Safety Data

• Hazardous Substances Data: 915302-21-5(Hazardous Substances Data)

Upstream product

• 37538-68-4 pyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione 
• 1462-86-8 3-amino-pyridine-2-carboxylic acid 
• 656801-64-8 methyl 3-isocyanatopyridine-2-carboxylate 
• 24195-07-1 pyridine-2,3-dicarboxylic acid 2-methyl ester 
• 37538-68-4 pyrido<3,2-d>pyrimidine-2,4(1H,3H)-dione 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 27507-08-0 3-(4-methoxybenzyl)pyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione 
• 39551-54-7 2,4-dichloropyrido[3,2-d]-pyrimidine 

Downstream Products

• 1189147-55-4 4-chloro-N-(pyrido[3,2-d]pyrimidin-2-yl)benzamide 
• 1189147-45-2 2-(2-chlorophenylamino)pyrido[3,2-d]pyrimidine 
• 1189147-37-2 2-(phenylamino)pyrido[3,2-d]pyrimidine 
• 1189147-39-4 2-(4-methoxyphenylamino)pyrido[3,2-d]pyrimidine 
• 1189147-42-9 2-(4-chlorophenylamino)pyrido[3,2-d]pyrimidine 
• 1189147-53-2 N-(pyrido[3,2-d]pyrimidin-2-yl)benzamide 
• 1189147-61-2 benzyl N-(pyrido[3,2-d]pyrimidin-2-yl)carbamate 

Relevant articles and documents

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

Efficient synthesis of 2-substituted pyrido[3,2-d]pyrimidines involving SNAr and palladium-catalyzed cross-coupling reactions

The efficient and original synthesis of various 2-substituted pyrido[3,2-d]pyrimidines is reported. Starting from 2,4-dichloropyrido [3,2-d]pyrimidine, a regioselective pallado-dehalogenation led to 2-chloropyrido[3,2-d]pyrimidine, which was used in SNAr and palladium-catalyzed cross-coupling reactions in order to afford highly functionalized products in very good yields. Georg Thieme Verlag Stuttgart.