91547-65-8Relevant articles and documents
A METHOD OF PRODUCING 5-HYDROXYPYRIDINE-2-CARBOXYLIC ACID FROM ALGINATE
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Page/Page column 22-23, (2012/11/06)
The present application provides methods for converting alginate into 5-hydroxypyridine- 2-carboxylic acid (5-HPA) using an alginate lyase and a recombinant oligoalginate lyase. The alginate lyase breaks down alginate into oligoalginate. The oligoalginate lyase breaks down the oligoalginate into monomers such as 4-deoxy-L-erythro-hexoseulose uronate (DEHU), which serves as a precursor for conversion into 5-HPA. The addition of ammonia or an ammonium ion further drives the conversion of DEHU into 5-HPA.