915759-45-4 Usage
Description
Benzenesulfonamide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)-, also known as WAY-316606, is a chemical compound that functions as an inhibitor of secreted frizzled-related protein 1 (sFRP-1) with an IC50 of 0.5 μM. It is characterized by its ability to enhance Wnt signaling in U2OS osteosarcoma cells, with an EC50 of 0.65 μM. Additionally, it has been observed to increase total bone area in a murine calvarial organ culture assay when applied at concentrations above 0.1 nM.
Uses
Used in Pharmaceutical Research:
WAY-316606 is utilized as a research tool in the development of pharmaceuticals targeting the Wnt signaling pathway. Its ability to increase Wnt signaling makes it a valuable compound for studying the effects of modulating this pathway in various diseases and conditions.
Used in Bone Regeneration Applications:
In the field of bone regeneration, WAY-316606 is used to stimulate bone growth and healing. Its capacity to increase total bone area in murine calvarial organ culture assays suggests potential applications in treating conditions that involve bone loss or promoting bone repair.
Used in Osteosarcoma Research:
WAY-316606 is also employed in the study of osteosarcoma, a type of bone cancer. Its effects on Wnt signaling in U2OS osteosarcoma cells provide insights into the role of this pathway in the development and progression of the disease, potentially leading to the discovery of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 915759-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,5,7,5 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 915759-45:
(8*9)+(7*1)+(6*5)+(5*7)+(4*5)+(3*9)+(2*4)+(1*5)=204
204 % 10 = 4
So 915759-45-4 is a valid CAS Registry Number.