915799-67-6

Basic information

• Product Name: 1-(Benzyloxy)-4-(difluoromethyl)benzene97%
• Synonyms: 1-(Benzyloxy)-4-(difluoromethyl)benzene97%
• CAS NO: 915799-67-6
• Molecular Formula: C₁₄H₁₂F₂O
• Molecular Weight: 234.25
• Mol File: 915799-67-6.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Benzyloxy)-4-(difluoromethyl)benzene97%(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Benzyloxy)-4-(difluoromethyl)benzene97%(915799-67-6)
• EPA Substance Registry System: 1-(Benzyloxy)-4-(difluoromethyl)benzene97%(915799-67-6)

Safety Data

• Hazardous Substances Data: 915799-67-6(Hazardous Substances Data)

Usage

Purity

97%

Industry Applications

Pharmaceutical and agrochemical industries

Use

Intermediate for the synthesis of various compounds

Stability

Stable under normal temperatures and pressures

Hazards

Eye and skin irritation upon contact

Safety Precautions

Handle and store with care, following safety guidelines to mitigate potential risks

Upstream product

• 65864-64-4 trimethyl(difluoromethyl)silane 
• 19578-68-8 4-(4-benzyloxyphenyl) iodide 
• 123-08-0 4-hydroxy-benzaldehyde 
• 100-39-0 benzyl bromide 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 1511-62-2 bromodifluoromethane 
• 146631-00-7 [4-(benzyloxy)phenyl]boronic acid 
• 75-45-6 Chlorodifluoromethane 
• 667-27-6 Ethyl bromodifluoroacetate 

Downstream Products

• 403648-76-0 4-(difluoromethyl)phenol 

Relevant articles and documents

Ph2S/selectfluor-promoted deoxydifluorination of aldehydes

The installation of a HCF2 group is a research area that has received increasing attention, and deoxydifluorination of aldehydes have served as an attractive protocol due to the wide availability of aldehydes. Herein we describe a Ph2/sub

Method for preparing alpha-aryl/heteroaryl/alkenyl-alpha,alpha-difluoromethyl compounds

The invention discloses a method for preparing alpha-aryl/heteroaryl/alkenyl-alpha,alpha-difluoromethyl compounds. The preparation method for the alpha-aryl/heteroaryl/alkenyl-alpha,alpha-difluoromethyl compounds as shown in a formula C which is described

Containing fluoromethyl compound and its preparation method

The invention discloses a compound containing difluromethylation and a preparation method therefor. The invention provides a preparation method of a compound RCF2H containing the difluromethylation. The preparation method comprises the following steps of: under the protection of inert gas, performing a coupling reaction on a compound RX and trimethyl difluromethylation silicon in an organic solvent under the existing conditions of a palladium catalyst, a ligand and alkali so as to obtain the compound RCF2H containing the difluromethylation. Through the adoption of the difluromethylation reaction of the compound disclosed by the invention, the difluromethylation of the compound with various aryl halogen compounds such as aryl iodide, aryl bromide and natural products (such as estrone or vitamin E) can be realized, the conditions of the type of reactions are mild, raw materials are cheap and easy to obtain, the conversion rate of the reaction is high, the compatibility of base groups is good, and the compound has a good market application prospect. RX+TMSCF2H -> RCF2H