916174-19-1

Basic information

• Product Name: 4-(2,4-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridine
• Synonyms: 4-(2,4-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 916174-19-1
• Molecular Weight: 222.29
• Mol File: 916174-19-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2,4-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,4-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridine(916174-19-1)
• EPA Substance Registry System: 4-(2,4-dimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridine(916174-19-1)

Safety Data

• Hazardous Substances Data: 916174-19-1(Hazardous Substances Data)

Upstream product

• 55499-44-0 2,4-dimethylbenzeneboronic acid 
• 55052-28-3 4-chloro-7-azaindole 

Relevant articles and documents

1H-PYRROLO[2,3-B]PYRIDINE DERIVATIVES USEFUL AS HSP90 INHIBITORS

Compounds of formula (I) have HSP90 inhibitory activity: ring A is an aryl or heteroaryl ring or ring system; R1 is hydrogen, fluoro, chloro, bromo, or a radical of formula (1A): -X-Alk1-(Z)m-(Alk2)n-Q (IA) wherein X is a bond, -O-, -S-, -S(O)-, -SO2-, or -NH-, Z is -O-, -S-, -(C=O)-, -(C=S)-, -S(O)-, -SO2-, -NRA-, or, in either orientation -C(=O)O-, -C(=O)NRA-, -C(=S)NRA-, -SO2NRA-, -NRAC(=O)-, or -NRASO2- wherein RA is hydrogen or C1-C6 alkyl in which one or more hydrogens is optionally substituted by fluorine;Alk1 and AIk2 are optionally substituted divalent C1-C3 alkylene:or C2-C3 alkenylene radicals, m and n are independently 0 or 1, and Q is hydrogen or an optionally substituted carbocyclic or heterocyclic radical; R2 is cyano (-CN), fluoro, chloro, bromo, methyl, ethyl, -OH, -CH2OH, -C(=O)NH2,-C(=O)H, -C(=O)CH3, or -NH2; R3 and R4 are independently selected from hydrogen, fluoro, chloro, bromo, cyano (-CN), C1-C3alkyl optionally substituted with one or more fluorine substituents, C1-C3alkoxy optionally substituted with one or more fluorine substituents, -CH=CH2, -C≡CH, cyclopropyl and -NH2, or R3 and R4 together represent methylenedioxy (-OCH2O-) or ethylenedioxy (-OCH2CH2O-) in either of which one or more hydrogens are optionally replaced by fluorine; S1 is as defined in the description.