916225-97-3Relevant articles and documents
Total Synthesis of (±)-Thebainone A by Intramolecular Nitrone Cycloaddition
Hahn, Christian,Hennig, André,J?ger, Anne,Küttler, Thomas,Metz, Peter,Wang, Yuzhou
supporting information, (2020/04/21)
Using an intramolecular nitrone cycloaddition and a Heck cyclization as the crucial transformations, a total synthesis of the racemic morphine alkaloid thebainone A was accomplished in 22 steps commencing with isovanillin.
Total synthesis of (±)-morphine
Uchida, Kenji,Yokoshima, Satoshi,Kan, Toshiyuki,Fukuyama, Tohru
experimental part, p. 1219 - 1234 (2010/10/03)
The morphinan skeleton was effectively synthesized by an intramolecular Mannich-type reaction. Further transformation led to the total synthesis of morphine.