916347-56-3

Basic information

• Product Name: (2R,4R)-4-[(benzylthio)methyl]-2-(4-fluorophenyl)-2-(trifluoromethyl)-1,3-oxazolidine
• Synonyms: (2R,4R)-4-[(benzylthio)methyl]-2-(4-fluorophenyl)-2-(trifluoromethyl)-1,3-oxazolidine
• CAS NO: 916347-56-3
• Molecular Weight: 371.399
• Mol File: 916347-56-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4R)-4-[(benzylthio)methyl]-2-(4-fluorophenyl)-2-(trifluoromethyl)-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-4-[(benzylthio)methyl]-2-(4-fluorophenyl)-2-(trifluoromethyl)-1,3-oxazolidine(916347-56-3)
• EPA Substance Registry System: (2R,4R)-4-[(benzylthio)methyl]-2-(4-fluorophenyl)-2-(trifluoromethyl)-1,3-oxazolidine(916347-56-3)

Safety Data

• Hazardous Substances Data: 916347-56-3(Hazardous Substances Data)

Upstream product

• 655-32-3 2,2,2-trifluoro-1-(4-fluorophenyl)ethanone 
• 85803-43-6 (1S)-1-(benzylthiomethyl)-2-hydroxyethylamine 

Downstream Products

• 916347-58-5 3-(benzylsulfonyl)-N-[(1R)-3-cyclopropyl-1-(4-fluorophenyl)-1-(trifluoromethyl)prop-2-yn-1-yl]-L-alanine 
• 916347-57-4 (2R)-3-(benzylthio)-2-{[(1R)-3-cyclopropyl-1-(4-fluorophenyl)-1-(trifluoromethyl)prop-2-yn-1-yl]amino}propan-1-ol 

Relevant articles and documents

FLUOROALKYLAMINE DERIVATIVES AS CATHEPSIN INHIBITORS

The present invention provides compounds of formula I which are inhibitors of cathepsin S and as such are useful in the prevention and treatment of cathepsin S dependent diseases and conditions including, but not limited to, chronic obstructive pulmonary disease (COPD) and pain.