916515-28-1

Basic information

• Product Name: (S)-2-trifluoromethanesulfonyloxybutyrolactone
• Synonyms: (S)-2-trifluoromethanesulfonyloxybutyrolactone
• CAS NO: 916515-28-1
• Molecular Weight: 234.153
• Mol File: 916515-28-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-trifluoromethanesulfonyloxybutyrolactone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-trifluoromethanesulfonyloxybutyrolactone(916515-28-1)
• EPA Substance Registry System: (S)-2-trifluoromethanesulfonyloxybutyrolactone(916515-28-1)

Safety Data

• Hazardous Substances Data: 916515-28-1(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 52079-23-9 (3S)-3-hydroxydihydrofuran-2(3H)-one 

Downstream Products

• 916515-10-1 (R)-3-[3-({benzoxazol-2-yl[3-(4-methoxyphenoxy)propyl]amino}methyl)phenoxy]dihydrofuran-2(3H)-one 

Relevant articles and documents

PROCESSES FOR PRODUCTION OF OPTICALLY ACTIVE PPAR-ACTIVATING COMPOUNDS AND INTERMEDIATES FOR PRODUCTION THEREOF

The invention provides a process for producing an optically active butyric acid compound and a production intermediate therefor at high yield and high purity. The present invention provides a process for producing Compound (6), including reacting Compound (1) with optically active 2-trifluoromethanesulfonyloxybutyrolactone (2a) in the presence of a base or reacting optically active 2-hydroxybutyrolactone (2b) under Mitsunobu reaction conditions, to thereby form Compound (3); reacting Compound (3) with an alcohol and a halogenating agent, to thereby form Compound (4) ; dehalogenating Compound (4), to thereby form Compound (5); and de-esterifying Compound (5).