916763-94-5

Basic information

• Product Name: (2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol
• Synonyms: (2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol
• CAS NO: 916763-94-5
• Molecular Weight: 362.426
• Mol File: 916763-94-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol(916763-94-5)
• EPA Substance Registry System: (2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol(916763-94-5)

Safety Data

• Hazardous Substances Data: 916763-94-5(Hazardous Substances Data)

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 220652-49-3 (R)-N-Boc-O-tertbutyldimethylsilyl-3,4-dehydroprolinol 
• 115378-31-9 tert-butyl (4R)-2,2-dimethyl-4-vinyloxazolidine-3-carboxylate 
• 129514-85-8 (-)-tert-butyl [(1R)-1-({[tert-butyl(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate 
• 89985-86-4 (R)-2-(N-tert-butoxycarbonylamino)-3-buten-1-ol 
• 916763-87-6 (2R,1'S,3S,4S)-Nα-Boc-O-tert-butyldimethylsilyl-3,4-(dibenzylaminomethano)prolinol 
• 916763-88-7 (2R,1'S,3S,4S)-Nα-Boc-3,4-(dibenzylaminomethano)prolinol 
• 916763-86-5 (R)-N-allyl-N-Boc-O-(tert-butyldimethylsilyl)vinylglycinol 

Downstream Products

• 1026363-06-3 Nα-Fmoc-3,4-(Z-aminomethano)prolinol 

Relevant articles and documents

An improved synthesis of 3,4-(aminomethano)proline and its incorporation into small oligopeptides

Starting from the readily available Garner aldehyde, a new synthesis of diastereomerically and enantiomerically pure 3,4-(aminomethano)prolinol (2R,1′S,3S,4S)-17 has been developed using simple and easily scalable transformations. The protected diamino al