916895-89-1Relevant articles and documents
Synthesis of 7-azaserotonin: Its photophysical properties associated with excited state proton transfer reaction
Wu, Pei-Wen,Hsieh, Wan-Ting,Cheng, Yi-Ming,Wei, Ching-Yen,Chou, Pi-Tai
, p. 14426 - 14427 (2006)
We report the synthesis of 3-(2-aminoethyl)-5-ol-1H-pyrrolo[2,3-b]pyridine (7-azaserotonin), which may potentially serve as an agonist or antagonist of serotonin receptors. In alcohols, the solvent (e.g., ethanol) catalyzed proton-transfer reaction takes place for 7-azaserotonin in the excited state, resulting in dual emission. Conversely, excited-state deprotonation takes place in neutral aqueous solution. The unique excitation behavior makes 7-azaserotonin versatile as a potential bioprobe. Copyright