917253-02-2

Basic information

• Product Name: pentafluorophenyl R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)tetrahydrothiazole-4-carboxylate
• Synonyms: pentafluorophenyl R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)tetrahydrothiazole-4-carboxylate
• CAS NO: 917253-02-2
• Molecular Weight: 574.569
• Mol File: 917253-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: pentafluorophenyl R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)tetrahydrothiazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: pentafluorophenyl R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)tetrahydrothiazole-4-carboxylate(917253-02-2)
• EPA Substance Registry System: pentafluorophenyl R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)tetrahydrothiazole-4-carboxylate(917253-02-2)

Safety Data

• Hazardous Substances Data: 917253-02-2(Hazardous Substances Data)

Upstream product

• 917252-91-6 R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)tetrahydrothiazole-4-carboxylic acid 
• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 133010-06-7 1,1-dimethylethyl S-N-(1-fluorocarbonyl-2-phenylethyl)carbamate 
• 67089-92-3 L-(-)-2,2-dimethylthiazolidine-4-carboxylic acid hydrochloride salt 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Downstream Products

• 917253-06-6 R-2,2-dimethyl-3-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)-N-(2-(4-nitrophenyl)ethyl)tetrahydrothiazole-4-carboxamide 

Relevant articles and documents

Effects of steric bulk and stereochemistry on the rates of?diketopiperazine formation from N-aminoacyl-2,2-dimethylthiazolidine-4-carboxamides (Dmt dipeptide amides)-a model for a new prodrug linker system

A peptide-like self-immolative molecular clip is required for release of active drugs from prodrugs by endopeptidases. Upon cleavage from the carrier, this clip must collapse and release the drug rapidly. A series of aminoacyl-5,5-dimethylthiaproline (Aaa