917392-75-7

Basic information

• Product Name: (2R)-2-benzyloxycarbonylamino-4-methyl-pentanoic acid benzylamide
• Synonyms: (2R)-2-benzyloxycarbonylamino-4-methyl-pentanoic acid benzylamide
• CAS NO: 917392-75-7
• Molecular Weight: 354.449
• Mol File: 917392-75-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-2-benzyloxycarbonylamino-4-methyl-pentanoic acid benzylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-benzyloxycarbonylamino-4-methyl-pentanoic acid benzylamide(917392-75-7)
• EPA Substance Registry System: (2R)-2-benzyloxycarbonylamino-4-methyl-pentanoic acid benzylamide(917392-75-7)

Safety Data

• Hazardous Substances Data: 917392-75-7(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 328-38-1 (R)-leucine 
• 28862-79-5 Z-D-Leu-OH 
• 100-46-9 benzylamine 

Downstream Products

• 917392-70-2 (2R)-2-butylamino-4-methyl-pentanoic acid benzylamide 
• 123636-09-9 (R)-2-Amino-4-methyl-pentanoic acid benzylamide 

Relevant articles and documents

Circular dichroism studies on absolute configuration assignment of peptidomimetics with a terminal chiral 3-arylpropionic acid unit

The relationship between the molecular structure of peptidomimetics 1 and their chiroptical properties has been studied using circular dichroism spectroscopy. It was demonstrated that the sign of the Cotton effects occurring around 230 and 270 nm enables the direct assignment of stereochemistry at C-1 and C-3 carbon atoms. The TD-DFT calculations of the circular dichroism (CD) spectrum of one of the model compounds confirm the absolute stereochemistry assignment made experimentally. Thus, CD spectroscopy proved to be a simple, reliable and general tool for the determination of the absolute configuration of the stereogenic centers of peptidomimetics with a terminal 3-arylpropionic group.