917477-33-9

Basic information

• Product Name: 2-(2-bromophenoxy)benzoic acid
• Synonyms: 2-(2-bromophenoxy)benzoic acid
• CAS NO: 917477-33-9
• Molecular Formula: C₁₃H₉BrO₃
• Molecular Weight: 293.12
• Mol File: 917477-33-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-bromophenoxy)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromophenoxy)benzoic acid(917477-33-9)
• EPA Substance Registry System: 2-(2-bromophenoxy)benzoic acid(917477-33-9)

Safety Data

• Hazardous Substances Data: 917477-33-9(Hazardous Substances Data)

Upstream product

• 95-56-7 2-hydroxybromobenzene 
• 394-47-8 2-fluorobenzonitrile 
• 1380084-77-4 2-(2-bromophenoxy)benzoic acid methyl ester 
• 537036-78-5 2-(2-bromophenoxy)benzonitrile 

Downstream Products

• 132-64-9 dibenzofuran 
• 89827-45-2 4-bromodibenzofuran 
• 74104-10-2 4-phenyldibenzo[b,d]furan 

Relevant articles and documents

Electrochemical Reductive Smiles Rearrangement for C-N Bond Formation

A conceptually new and synthetically valuable radical Smiles rearrangement reaction is reported under undivided electrolytic conditions. This protocol employs an entirely new strategy for the electrochemical radical Smiles rearrangement. Remarkably, an amidyl radical generated from the cleavage of the N-O bond under reductive electrolytic conditions plays a crucial role in this transformation. Various hydroxylamine derivatives bearing different substituents are suitable in this electrochemical transformation, furnishing the corresponding amides in up to 86% yield.

Efficient Aryl Migration from an Aryl Ether to a Carboxylic Acid Group To Form an Ester by Visible-Light Photoredox Catalysis

We have developed a highly efficient aryl migration from an aryl ether to a carboxylic acid group through retro-Smiles rearrangement by visible-light photoredox catalysis at ambient temperature. Transition metals and a stoichiometric oxidant and base are avoided in the transformation. Inspired by the high efficiency of this transformation and the fundamental importance of C?O bond cleavage, we developed a novel approach to the C?O cleavage of a biaryl ether to form two phenolic compounds, as demonstrated by a one-pot, two-step gram-scale reaction under mild conditions. The aryl migration exhibits broad scope and can be applied to the synthesis of pharmaceutical compounds, such as guacetisal. Primary mechanistic studies indicate that the catalytic cycle occurs by a reductive quenching pathway.

TRICYCLIC OPIOID MODULATORS

The invention is directed to compounds of Formula (I) useful as delta and mu opioid receptor modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also