91774-25-3 Usage
Description
[2-(TRIMETHYLAMMONIUM)ETHYL] METHANETHIOSULFONATE BROMIDE is a white crystalline powder that is known for its specific and rapid reaction with thiols to form mixed disulfides. This unique property makes it a valuable tool in probing the structures of various biological channels and receptors.
Uses
Used in Biochemical Research:
[2-(TRIMETHYLAMMONIUM)ETHYL] METHANETHIOSULFONATE BROMIDE is used as a reagent for probing the structures of important biological channels and receptors, such as the ACh receptor channel, the GABAA receptor channel, and lactose permease. Its specific and rapid reaction with thiols allows researchers to gain insights into the molecular mechanisms and functions of these channels and receptors, contributing to a better understanding of their roles in various biological processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [2-(TRIMETHYLAMMONIUM)ETHYL] METHANETHIOSULFONATE BROMIDE can be used as a starting material or intermediate in the synthesis of potential drug candidates targeting the aforementioned channels and receptors. Its ability to form mixed disulfides with thiols can be exploited to develop novel therapeutic agents that modulate the activity of these targets, potentially leading to the discovery of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 91774-25-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,7,7 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 91774-25:
(7*9)+(6*1)+(5*7)+(4*7)+(3*4)+(2*2)+(1*5)=153
153 % 10 = 3
So 91774-25-3 is a valid CAS Registry Number.
91774-25-3Relevant articles and documents
Altering the specificity of subtilisin Bacillus lentus through the introduction of positive charge at single amino acid sites
Davis, Benjamin G.,Khumtaveeporn, Kanjai,Bott, Richard R.,Jones, J.Bryan
, p. 2303 - 2311 (2007/10/03)
The use of methanethiosulfonates as thiol-specific modifying reagents in the strategy of combined site-directed mutagenesis and chemical modification allows virtually unlimited opportunities for creating new protein surface environments. As a consequence
