917771-41-6Relevant articles and documents
Hydroxypurine compound and use thereof
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Paragraph 0503; 0504; 0505; 0506, (2016/10/08)
The invention discloses a hydroxypurine compound and a use of the hydroxypurine compound as a PDE2 or TNFa inhibitor and concretely discloses a compound shown in the formula (I) and its tautomer or pharmaceutically acceptable salt.
ROR GAMMA (RORY) MODULATORS
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Paragraph 0152, (2016/12/22)
The present invention relates to novel compounds according to Formula I or a pharmaceutically acceptable salt thereof wherein the variables are as defined in the claims. The compounds can be used as inhibitors of RORγ and are useful for the treatment of R
BTK protein kinase inhibitors
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Page/Page column 63, (2009/05/29)
This application discloses pyridine and pyrimidine compounds according to formula I wherein R1, R2, R3, R4, R5, X1 and A are as described herein which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of formula I and at least one carrier, diluent or excipient.