917896-43-6 Usage
General Description
BHF 177 is a synthetic chemical compound that acts as a potent and selective antagonist of the bradykinin B1 receptor. It is known for its ability to block the effects of bradykinin, a peptide involved in various physiological processes such as inflammation, blood pressure regulation, and pain sensation. BHF 177 has shown promise as a potential therapeutic agent for conditions such as chronic pain, inflammation, and cardiovascular diseases. Its high affinity and selectivity for the B1 receptor make it a valuable tool for studying the role of bradykinin in different biological processes and for developing new medications targeting this receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 917896-43-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,7,8,9 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 917896-43:
(8*9)+(7*1)+(6*7)+(5*8)+(4*9)+(3*6)+(2*4)+(1*3)=226
226 % 10 = 6
So 917896-43-6 is a valid CAS Registry Number.
917896-43-6Relevant articles and documents
Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABAB receptors
Guery, Sebastien,Floersheim, Philipp,Kaupmann, Klemens,Froestl, Wolfgang
, p. 6206 - 6211 (2008/04/03)
The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABAB receptors is presented.