91821-00-0

Basic information

• Product Name: 4-ethyl-3,5-dimethyl-1-phenyl-1H-pyrazole
• Synonyms: 4-ethyl-3,5-dimethyl-1-phenyl-1H-pyrazole
• CAS NO: 91821-00-0
• Molecular Weight: 200.283
• Mol File: 91821-00-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-ethyl-3,5-dimethyl-1-phenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl-3,5-dimethyl-1-phenyl-1H-pyrazole(91821-00-0)
• EPA Substance Registry System: 4-ethyl-3,5-dimethyl-1-phenyl-1H-pyrazole(91821-00-0)

Safety Data

• Hazardous Substances Data: 91821-00-0(Hazardous Substances Data)

Upstream product

• 1540-34-7 3-ethyl-2,4-pentanedione 
• 100-63-0 phenylhydrazine 

Relevant articles and documents

Efficient Copper-Catalyzed Synthesis of Substituted Pyrazoles at Room Temperature

An efficient method for the synthesis of pyrazoles through a copper-catalyzed condensation reaction has been developed. The new catalytic system not only maintained a broad substrate scope but was also active under acid-free reaction conditions, overcoming the conventional requirement for an acid-catalyzed system. Furthermore, the copper catalyst enabled this reaction to be performed at room temperature and in a short reaction time.

Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst

This invention relates to the use of nano-organocatalysts, and, more specifically, to the use of magnetic nanomaterial-supported organocatalysts. It is an object of the present invention to provide “green” catalysts and protocols. According to one embodiment of the invention, a nano-organocatalyst in the form of a magnetic nanomaterial-supported organocatalyst is provided. According to other embodiments of the invention, glutathione and cysteine are provided as organocatalysts and magnetic nanomaterial-supported glutathione and magnetic nanomaterial-supported cysteine are provided for use as nano-organocatalysts. According to another embodiment of the invention, a method of using a recyclable magnetic nanomaterial-supported organocatalyst using a totally benign aqueous protocol, without using any organic solvent in the reaction or during the workup, is provided. According to a further embodiment of the invention, a recyclable magnetic nanomaterial-supported organocatalyst for various organocatalytic reactions, including but not limited to Paal-Knorr reactions, aza-Michael addition and pyrazole synthesis, is provided.

Greener and rapid access to bio-active heterocycles: room temperature synthesis of pyrazoles and diazepines in aqueous medium

An expeditious room temperature synthesis of pyrazoles and diazepines by condensation of hydrazines/hydrazides and diamines with various 1,3-diketones is described. This greener protocol was catalyzed by polystyrene supported sulfonic acid (PSSA) and proceeded efficiently in water in the absence of any organic solvent within 1-2 min.