918524-93-3

Basic information

• Product Name: 4-(benzyloxy)-2,6-difluorobenzaldehyde
• Synonyms: 4-(benzyloxy)-2,6-difluorobenzaldehyde;2,6-difluoro-4-(phenylmethoxy)Benzaldehyde
• CAS NO: 918524-93-3
• Molecular Formula: C14H10F2O2
• Molecular Weight: 248
• Mol File: 918524-93-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 338.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.278±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-(benzyloxy)-2,6-difluorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2,6-difluorobenzaldehyde(918524-93-3)
• EPA Substance Registry System: 4-(benzyloxy)-2,6-difluorobenzaldehyde(918524-93-3)

Safety Data

• Hazardous Substances Data: 918524-93-3(Hazardous Substances Data)

Usage

General Description

4-(benzyloxy)-2,6-difluorobenzaldehyde is a chemical compound with the molecular formula C15H11F2O2. It is a benzaldehyde derivative with two fluorine atoms and a benzyloxy group attached to the benzene ring. 4-(benzyloxy)-2,6-difluorobenzaldehyde is commonly used as a building block in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. It has also been studied for its potential use in the development of novel materials and as a precursor in the production of specialty chemicals. The presence of the benzyloxy and difluoro groups in its structure provides unique reactivity and properties, making it an important intermediate in the synthesis of complex organic molecules.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 176175-97-6 1-benzyloxy-3,5-difluorobenzene 
• 532967-21-8 2,6-difluoro-4-hydroxybenzaldehyde 
• 100-39-0 benzyl bromide 

Relevant articles and documents

Highly Stereoselective Formation of a Spiro Center by a 1,4-Addition/Elimination Reaction of 3,5-Difluorocyclohexa-2,5-dienones

Spirocyclic 3,5-difluorocyclohexa-2,5-dienones possessing a triisopropylsiloxy-containing cyclic ether appendage were synthesized by oxidative dearomatization of the corresponding phenols. By group selectivity in the nucleophilic 1,4-addition/elimination reaction, highly stereoselective formation of the spiro center was successfully achieved. This reaction might provide access to total syntheses of (+)-bisdechlorogeodin and (+)-geodin with complete control of the formation of the spirocyclic structure.

NOVEL PYRROLOPYRIMIDINE COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME, ESPECIALLY AGENT FOR PREVENTION AND/OR TREATMENT OF TUMORS ETC BASED ON NAE INHIBITORY EFFECT

An object to be solved by the present invention is to provide a novel pyrrolopyrimidine compound or a salt thereof having an NAE inhibitory action and a cell growth inhibitory effect. The present invention provides a compound or a salt thereof represented by Formula (A), as well as an NAE inhibitor, a pharmaceutical composition, and an antitumor agent comprising the compound or a salt thereof as an active ingredient.