918643-33-1

Basic information

• Product Name: 7-(2-fluoro-4-nitrophenoxy)-2-iodothieno[3,2-b]pyridine
• Synonyms: 7-(2-fluoro-4-nitrophenoxy)-2-iodothieno[3,2-b]pyridine
• CAS NO: 918643-33-1
• Molecular Weight: 416.171
• Mol File: 918643-33-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-(2-fluoro-4-nitrophenoxy)-2-iodothieno[3,2-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(2-fluoro-4-nitrophenoxy)-2-iodothieno[3,2-b]pyridine(918643-33-1)
• EPA Substance Registry System: 7-(2-fluoro-4-nitrophenoxy)-2-iodothieno[3,2-b]pyridine(918643-33-1)

Safety Data

• Hazardous Substances Data: 918643-33-1(Hazardous Substances Data)

Upstream product

• 403-19-0 2-fluoro-4-nitrophenol 
• 602303-26-4 7-chloro-2-iodo-[3,2-b]thienopyridine 

Downstream Products

• 1187214-14-7 4-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)benzaldehyde 
• 1187214-15-8 N-(4-(7-(2-fluoro-4-nitrophenoxy)thieno[3.2-b]pyridin-2-yl)benzyl)-2-(2-(2-methoxyethoxy)ethoxy)ethanamine 
• 1187214-20-5 N-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)acetamide 
• 1187214-19-2 N-(4-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)acetamide 
• 1187214-17-0 tert-butyl 4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyndin-2-yl)benzyl(2-(2-(2-methoxyethoxy)ethoxy)ethyl)carbamate 
• 1187214-16-9 tert-butyl 4-(7-(2-fluoro-4-mtrophenoxy)thieno[3,2-b]pyridin-2-yl)benzyl(2-(2-(2-methoxyethoxy)ethoxy)ethyl)carbamate 
• 1187212-89-0 1-(4-(2-(4-5,8,11-trioxa-2-azadodecylphenyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-3-(5-methylisoxazol-3-yl)urea 
• 1187212-90-3 N-(4-(7-(2-fluoro-4-(3-(5-methylisoxazol-3-yl)ureido)phenoxy)thieno[3,2-b]pyridin-2-yl)benzyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)acetamide 
• 1187214-18-1 tert-butyl 4-(7-(2-fluoro-4-(3-(5-methylisoxazol-3-yl)ureido)phenoxy)thieno[3,2-b]pyridin-2-yl)benzyl(2-(2-(2-methoxyethoxy)ethoxy)ethyl)carbamate 
• 1127329-37-6 5-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)furan-2-carbaldehyde 
• 918643-34-2 6-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)nicotinaldehyde 

Relevant articles and documents

PROCESSES AND INTERMEDIATES FOR PREPARING FUSED HETEROCYCLIC KINASE INHIBITORS

The invention relates to processes and intermediates for manufacturing fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, and to processes and intermediates for preparing intermediates that are useful in the manufacture of fused heterocyclic-type kinase inhibitor compounds, particularly at an industrial level The processes are aimed at ultimately forming compounds of the formula (A) where M is thieno[3,2,b]pyridinyl as shown, the group D is a ring or ring system, preferably pyridine, and the group Z, Ar, and G are as defined herein Such compounds can act to inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signalling, for example, the inhibition of VEGF receptor signalling and HGF receptor signalling.