918961-64-5Relevant articles and documents
Total synthesis of narbonolide and biotransformation to pikromycin
Venkatraman, Lakshmanan,Salomon, Christine E.,Sherman, David H.,Fecik, Robert A.
, p. 9853 - 9856 (2007/10/03)
An improved total synthesis of narbonolide and its biotransformation to pikromycin is reported. This total synthesis utilized an intramolecular Nozaki-Hiyama-Kishi coupling that significantly improved macrocyclization yields (90-96%) and allowed for diffe