91897-97-1

Basic information

• Product Name: 2-amino-9-[(2-hydroxyethoxy)methyl]-8-methyl-3,9-dihydro-6H-purin-6-one
• Synonyms: 2-amino-9-[(2-hydroxyethoxy)methyl]-8-methyl-9H-purin-6-ol; 9H-purin-6-ol, 2-amino-9-[(2-hydroxyethoxy)methyl]-8-methyl-
• CAS NO: 91897-97-1
• Molecular Formula: C₉H₁₃N₅O₃
• Molecular Weight: 239.2312
• Mol File: 91897-97-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 573°C at 760 mmHg
• Flash Point: 300.4°C
• Density: 1.67g/cm³
• Vapor Pressure: 5.7E-14mmHg at 25°C
• Refractive Index: 1.73
• CAS DataBase Reference: 2-amino-9-[(2-hydroxyethoxy)methyl]-8-methyl-3,9-dihydro-6H-purin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-9-[(2-hydroxyethoxy)methyl]-8-methyl-3,9-dihydro-6H-purin-6-one(91897-97-1)
• EPA Substance Registry System: 2-amino-9-[(2-hydroxyethoxy)methyl]-8-methyl-3,9-dihydro-6H-purin-6-one(91897-97-1)

Safety Data

• Hazardous Substances Data: 91897-97-1(Hazardous Substances Data)

Upstream product

• 75-91-2 tert.-butylhydroperoxide 
• 59277-89-3 2-amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-ol 

Relevant articles and documents

Nucleic Acid Related Compounds. 47. Synthesis and Biological Activities of Pyrimidine and Purine "Acyclic" Nucleoside Analogues

Various acyclic, i.e., (2-hydroxyethoxy)methyl and (2-acetoxyethoxy)methyl, analogues of pyrimidine and purine nucleosides have been prepared evaluated for their antiviral, antimetabolic, and cytotoxic properties.All of the pyrimidine analogues, including (E)-5-(2-bromovinyl)-1-uracil (12) and its O-acetyl derivative (13), were virtually devoid of antiviral, cytotoxic, and antimetabolic activities.However, several of the 8-substituted derivatives of 9-guanine (acyclovir) had higher antiviral specificity in vitro than the parent drug.The 8-methyl-, 8-amino-, 8-bromo-, and 8-iodoacyclovir derivatives have activities worthy of further investigation.