919784-70-6

Basic information

• Product Name: 1,1-dimethylethyl 3-[({3-[(1-methylethyl)oxy]-5-[(phenylmethyl)oxy]phenyl}carbonyl)amino]-1H-pyrazole-1-carboxylate
• Synonyms: 1,1-dimethylethyl 3-[({3-[(1-methylethyl)oxy]-5-[(phenylmethyl)oxy]phenyl}carbonyl)amino]-1H-pyrazole-1-carboxylate
• CAS NO: 919784-70-6
• Molecular Weight: 451.522
• Mol File: 919784-70-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl 3-[({3-[(1-methylethyl)oxy]-5-[(phenylmethyl)oxy]phenyl}carbonyl)amino]-1H-pyrazole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl 3-[({3-[(1-methylethyl)oxy]-5-[(phenylmethyl)oxy]phenyl}carbonyl)amino]-1H-pyrazole-1-carboxylate(919784-70-6)
• EPA Substance Registry System: 1,1-dimethylethyl 3-[({3-[(1-methylethyl)oxy]-5-[(phenylmethyl)oxy]phenyl}carbonyl)amino]-1H-pyrazole-1-carboxylate(919784-70-6)

Safety Data

• Hazardous Substances Data: 919784-70-6(Hazardous Substances Data)

Upstream product

• 863504-84-1 3-aminopyrazole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 919784-69-3 1,1-dimethylethyl 3-[({3-hydroxy-5-[(1-methylethyl)oxy]phenyl}carbonyl)amino]-1H-pyrazole-1-carboxylate 

Relevant articles and documents

NOVEL CRYSTALLINE COMPOUND

A novel crystalline form of 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1H-pyrazol-3-ylbenzamide is described in the specification. This compound is a glucokinase (GLK or GK) activator and useful as a pharmaceutical agent in the treatment or prevention of a disease or medical condition mediated through GLK, leading to a decreased glucose threshold for insulin secretion. Processes for the manufacture of the crystalline form, pharmaceutical compositions comprising the crystalline form and the use of the crystalline form in medical treatment are also described.