919787-07-8Relevant articles and documents
Synthesis and c-Src inhibitory activity of imidazo[1,5-a]pyrazine derivatives as an agent for treatment of acute ischemic stroke
Mukaiyama, Harunobu,Nishimura, Toshihiro,Kobayashi, Satoko,Ozawa, Tomonaga,Kamada, Noboru,Komatsu, Yoshimitsu,Kikuchi, Shinji,Oonota, Hideki,Kusama, Hiroshi
, p. 868 - 885 (2007/10/03)
We synthesized and evaluated a series of C-5 substituted imidazo[1,5-a]pyrazine derivatives to identify potent c-Src inhibitors as potential therapeutic agents for acute ischemic stroke. Among these compounds, compound 14c·HCl demonstrated remarkable cent