92033-74-4

Basic information

• Product Name: L-Leucine, N-[(phenylamino)carbonyl]-
• CAS NO: 92033-74-4
• Molecular Formula: C13H18N2O3
• Molecular Weight: 250.298
• Mol File: 92033-74-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-Leucine, N-[(phenylamino)carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, N-[(phenylamino)carbonyl]-(92033-74-4)
• EPA Substance Registry System: L-Leucine, N-[(phenylamino)carbonyl]-(92033-74-4)

Safety Data

• Hazardous Substances Data: 92033-74-4(Hazardous Substances Data)

Upstream product

• 65-85-0 benzoic acid 
• 61-90-5 L-leucine 
• 86298-24-0 N-phenyl-1H-benzo[d][1,2,3]triazole-1-carboxamide 
• 2748-02-9 L-leucine tert-butyl ester hydrochloride 
• 21691-53-2 L-leucine tert-butyl ester 
• 1259946-52-5 N-(phenylcarbamoyl)-leucine tert-butyl ester 
• 35661-60-0 Fmoc-Leu-OH 
• 103-71-9 phenyl isocyanate 
• 168471-11-2 (S)-4-Methyl-2-(3-phenyl-ureido)-pentanoic acid benzyl ester 
• 2899-43-6 DL-leucine ethyl ester 
• 88576-97-0 N-(N-phenylcarbamoyl-leucyl)-glycine 

Downstream Products

• 1259946-59-2 (N-phenylcarbamoyl)leucine 1,2-dimethylhydrazide 
• 1259945-85-1 N-(phenylcarbamoyl)-leucyl-methylazaalanine-nitrile 
• 104060-50-6 phenylcarbamoyl-L-leucine methyl ester 
• 168471-14-5 5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-4-methyl-2-(3-phenyl-ureido)-pentanoylamino]-ethyl}-oxazole-4-carboxylic acid benzyl ester 
• 2221-06-9 5-isobutyl-3-phenylimidazolidine-2,4-dione 

Relevant articles and documents

One-pot preparation of carbamoyl benzotriazoles and their applications in the preparation of ureas, hydrazinecarboxamides and carbamic esters

Carbamoyl benzotriazoles were conveniently synthesized in one-pot from carboxylic acids, diphenyl phosphorazidate (DPPA) and 1H-benzotriazole (BtH). The reactivity and applications of carbamoyl benzotriazoles were also explored. Carbamoyl benzotriazoles react smoothly with amino acids, hydrazines and alcohols, thus providing facile access to the corresponding ureas, hydrazinecarboxamides and carbamic esters, respectively, in good to excellent yields.

Solid-phase synthesis of oligourea peptidomimetics

A procedure for the solid-phase synthesis of oligourea peptidomimetics starting from Boc-protected monomers is described. The compounds are prepared on Tentagel resin and can be obtained selectively rather as the C-terminal free acids with UV irradiation

Aldehyde derivatives and their use as calpain inhibitors

Aldehyde derivatives with a specific calpain inhibiting activity and a platelet-aggregation inhibiting effect with formula (I) or formula (II): wherein R1 represents an aromatic hydrocarbon group, a heterocyclic group, or a group of-X-R3 in which X represents O,-S(O)m-(m = 0, 1, or 2), and R3 represents an aromatic hydrocarbon group, a heterocyclic group, or an alkyl group; Z represents R?-Y-or R?O-CH(R?)-in which Y represents a 3-to 7-membered nitrogen-containing saturated heterocyclic group, or a single cyclic saturated hydrocarbon group, R? represents an alkyl group, an alkenyl group, an alkynyl group, an acyl group, a sulfonyl group, an alkoxycarbonyl group, a carbamoyl group, or a thiocarbamoyl group, R? represents hydrogen, an alkyl group, or an aromatic hydrocarbon group, and R? represents an acyl group, a carbamoyl group, a thiocarbamoyl group, or an alkyl group; and n is an integer of 1 to 5. wherein R?, R?, R?, and R1? are defined in the specification.