92051-12-2

Basic information

• Product Name: 3'-Thymidylic acid, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 1,1-dioxido-1,2-benzisothiazol-3-yl 5-chloro-8-quinolinyl ester
• CAS NO: 92051-12-2
• Molecular Formula: C47H40ClN4O12PS
• Molecular Weight: 951.347
• Mol File: 92051-12-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3'-Thymidylic acid, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 1,1-dioxido-1,2-benzisothiazol-3-yl 5-chloro-8-quinolinyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-Thymidylic acid, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 1,1-dioxido-1,2-benzisothiazol-3-yl 5-chloro-8-quinolinyl ester(92051-12-2)
• EPA Substance Registry System: 3'-Thymidylic acid, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 1,1-dioxido-1,2-benzisothiazol-3-yl 5-chloro-8-quinolinyl ester(92051-12-2)

Safety Data

• Hazardous Substances Data: 92051-12-2(Hazardous Substances Data)

Upstream product

• 567-19-1 3-chloro-1,2-benzisothiazole 1,1-dioxide 
• 71933-71-6 O-8-(5-chloroquinolyl) phosphate 
• 92051-11-1 Phosphoric acid 5-chloro-quinolin-8-yl ester bis-(1,1-dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl) ester 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 

Relevant articles and documents

AN EFFICIENT PHOSPHORYLATING AGENT FOR THE SYNTHESIS OF NUCLEOSIDE 3'-PHOSPHODIESTER INTERMEDIATES IN OLIGONUCLEOTIDE SYNTHESIS

By using 3-chloro-1,2-benzoisothiazole 1,1-doxide (BIDCl), 5-chloro-8-quinolyl phosphate can be converted into an efficient phosphorylating agent (4), which can be used to synthesze nucleoside 3'-phosphodiester intermediates (2).Keywords - phosphorylation