92152-98-2

Basic information

• Product Name: 2-(2-chlorophenyl)-1-(4-chlorophenyl)ethanone
• CAS NO: 92152-98-2
• Molecular Formula: C₁₄H₁₀Cl₂O
• Molecular Weight: 265.1346
• Mol File: 92152-98-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 393.2°C at 760 mmHg
• Flash Point: 166.2°C
• Density: 1.289g/cm³
• Vapor Pressure: 2.16E-06mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 2-(2-chlorophenyl)-1-(4-chlorophenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chlorophenyl)-1-(4-chlorophenyl)ethanone(92152-98-2)
• EPA Substance Registry System: 2-(2-chlorophenyl)-1-(4-chlorophenyl)ethanone(92152-98-2)

Safety Data

• Hazardous Substances Data: 92152-98-2(Hazardous Substances Data)

Usage

Type of compound

Ketone derivative

Class of organic compounds

Acetophenone

Chirality

Chiral compound

Medical use

Anorectic or appetite suppressant

Treatment target

Obesity

Mechanism of action

Increases release of norepinephrine and dopamine in the brain

Effects

Reduced appetite and increased energy expenditure

Potential side effects

Insomnia, palpitations, and elevated blood pressure

Caution

Use with caution and under the supervision of a healthcare professional

Upstream product

• 2444-36-2 2'-chloro-benzeneacetic acid 
• 108-90-7 chlorobenzene 
• 623-03-0 4-Cyanochlorobenzene 
• 51512-09-5 2-(2-chlorophenyl)acetyl chloride 
• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 122-01-0 4-chloro-benzoyl chloride 
• 139326-89-9 N-(4-chlorobenzyl)-pyridinium bromide 
• 611-19-8 1-chloro-2-(chloromethyl)benzene 

Downstream Products

• 935456-45-4 1-(4-chlorophenyl)-2-(2-chlorophenyl)-3-(N,N-dimethylamino)-2-propen-1-one 
• 1202017-82-0 2-(4-chloro-phenyl)-3-(2-chloro-phenyl)-6-(2H-tetrazol-5-ylmethyl)-pyridine-5-carboxylic acid [(R)-1-(2-fluoro-phenyl)-ethyl]-amide 
• 1202017-69-3 2-(4-chloro-phenyl)-3-(2-chloro-phenyl)-6-cyanomethyl-pyridine-5-carboxylic acid [(R)-1-(2-fluoro-phenyl)-ethyl]-amide 
• 1202017-67-1 2-(4-chloro-phenyl)-3-(2-chloro-phenyl)-6-cyanomethyl-pyridine-5-carboxylic acid 
• 1202017-68-2 2-(4-chloro-phenyl)-3-(2-chloro-phenyl)-6-cyanomethyl-pyridine-5-carboxylic acid chloride 
• 94148-01-3 2-(2-chlorophenyl)-3-(4-chlorophenyl)-prop-1-en-3-one 
• 92153-28-1 2.4'-Dichlor-benzilsaeure 
• 25144-40-5 (E)-1-chloro-2-(4-chlorostyryl)benzene 
• 92291-61-7 1-<4-Chlorphenyl>-2-<2-chlorphenyl>-aethanol 
• 55510-24-2 1-(2-chlorophenyl)-2-(4-chlorophenyl)ethane-1,2-dione 
• 7504-28-1 1-chloro-2-((4-chlorophenyl)ethynyl)benzene 

Relevant articles and documents

New preparation of benzylic manganese chlorides by the direct insertion of magnesium into benzylic chlorides in the presence of MnCl2·2LiCl

Functionalized benzylic manganese chlorides were smoothly prepared by the direct insertion of magnesium into benzylic chlorides in the presence of MnCl2·2LiCl. Reactions with acid chlorides, aldehydes, an allyl bromide, and an enone proceed without any additional transition metal.

Synthesis, antileukemic and antiplatelet activities of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines

The synthesis, antileukemic and antiplatelet activity evaluation of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines are described. In general, it was found that compound 17o showed moderate antileukemic activity against MOLT3 human leukemic cancer cell lines. An arachidonic acid induced platelet aggregation effect on washed rat platelets was studied. Compound 17i was found to be the most potent. The antiplatelet properties may be mediated by interference with the arachidonic acid pathway.

An efficient and time saving microwave-assisted selenium dioxide oxidation of 1,2-diarylethanones

Selenium dioxide oxidation of 1,2-diarylethanones to corresponding diones by conventional method takes upto 8 hr. The same oxidation under microwave radiations using dimethylsulfoxide as solvent reduces the reaction time considerably (30 to 90 sec). The method reported is efficient and time saving.