92241-87-7Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS STING MODULATORS
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Paragraph 0088; 0096-0097, (2021/04/17)
Disclosed herein are heterocyclic compounds that may be used as STING modulators, process for synthesis and to uses of such compounds in treatment of various diseases including cancers.
TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS
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Page/Page column 104; 105, (2014/01/08)
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.
Substituted Heteroaryl Spiropyrrolidine MDM2 Antagonists
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Page/Page column 33, (2012/03/10)
There are provided compounds of the general formula wherein A, B, V, W, R1, R2, R3, R3, and R4, are as described herein and enantiomers and pharmaceutically acceptable salts thereof. The compounds are useful as anticancer agents.