922712-35-4Relevant articles and documents
Synthesis and biological activity of PTEN-resistant analogues of phosphatidylinositol 3,4,5-trisphosphate
Zhang, Honglu,Markadieu, Nicolas,Beauwens, Renaud,Erneux, Christophe,Prestwich, Glenn D.
, p. 16464 - 16465 (2007/10/03)
The activation of phosphatidylinositol 3-kinase (PI 3-K) and subsequent production of PtdIns(3,4,5)P3 launches a signal transduction cascade that impinges on a plethora of downstream effects on cell physiology. Control of PI 3-K and PtdIns(3,4,