922734-43-8 Usage
Description
(2R,6S)-rel-2,6-DiMethyl-4-(2-Methyl-3-phenylpropyl)Morpholine Hydrochloride is a morpholine derivative with the molecular formula C15H26ClNO. It is a chiral compound with two chiral centers, resulting in multiple stereoisomers. As a hydrochloride salt, it appears as a white crystalline solid. This chemical compound is often utilized as a pharmaceutical intermediate in the synthesis of various drugs and has potential medicinal properties for the development of new therapeutic agents for different medical conditions.
Uses
Used in Pharmaceutical Industry:
(2R,6S)-rel-2,6-DiMethyl-4-(2-Methyl-3-phenylpropyl)Morpholine Hydrochloride is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure and chiral centers allow it to be a key component in the development of new medications.
Used in Medicinal Chemistry Research:
As a compound with potential medicinal properties, (2R,6S)-rel-2,6-DiMethyl-4-(2-Methyl-3-phenylpropyl)Morpholine Hydrochloride is used in medicinal chemistry research to explore its therapeutic potential for various medical conditions. Its unique structure and chiral centers make it a promising candidate for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 922734-43-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,2,7,3 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 922734-43:
(8*9)+(7*2)+(6*2)+(5*7)+(4*3)+(3*4)+(2*4)+(1*3)=168
168 % 10 = 8
So 922734-43-8 is a valid CAS Registry Number.
922734-43-8Relevant articles and documents
Amorolfine hydrochloride preparation method
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Paragraph 0060-0064, (2019/01/08)
The invention provides an amorolfine hydrochloride preparation method which specifically comprises the following steps: putting a compound of formula IIa shown in the specification into an organic solvent, further putting an amidation catalyst, carrying out a stirring reaction, further adding cis-2,6-dimethyl morpholine, and carrying out a reaction so as to obtain a compound III; carrying out backflow stirring on the compound III in absolute methanol, adding magnesium chips in batches, and carrying out a reaction so as to obtain a compound IV; carrying out a reaction on the compound IV under the action of a reducing agent, thereby obtaining a compound V. The method is novel in process route, cheap and easy in raw material obtaining, low in cost, simple in process operation, short in production cycle, gentle in reaction condition, high in yield, good in product quality and applicable to industrial production.
PROCESS OF PRODUCING AMOROLFINE
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Page/Page column 8-13, (2008/06/13)
The present invention refers to an improved process of producing Amorolfine base, which is a compound of Formula (I) said process comprising the steps of: (i) contacting a compound of Formula (II) with a Friedel- Crafts catalyst at a temperature in the range of 20 to 30 °C; and (ii) adding one equivalent of 2-halogeno-2- methylbutane, characterised in that the reaction mixture obtained in step (i) is cooled to a temperature between -40 to -60 °C prior to step (ii).
